1,5-二氨基戊烷

一般危化品
1,5-二氨基戊烷结构式
1,5-二氨基戊烷结构式
常用名 1,5-二氨基戊烷 英文名 Cadaverine
CAS号 462-94-2 分子量 102.178
密度 0.9±0.1 g/cm3 沸点 179.0±8.0 °C at 760 mmHg
分子式 C5H14N2 熔点 9 °C
MSDS 中文版 美版 闪点 76.5±24.8 °C
符号 GHS05
GHS05
信号词 Danger

In vitro inhibition of lysine decarboxylase activity by organophosphate esters.

Biochem. Pharmacol. 92(3) , 506-16, (2014)

Organophosphate esters (OPEs), a major group of organophosphorus flame retardants, are regarded as emerging environmental contaminants of health concern. Amino acid decarboxylases catalyze the conversion of amino acids into polyamines that are essential for c...

Mechanistic studies on the flavin-dependent N⁶-lysine monooxygenase MbsG reveal an unusual control for catalysis.

Arch. Biochem. Biophys. 550-551 , 58-66, (2014)

The mechanism of Mycobacterium smegmatis G (MbsG), a flavin-dependent l-lysine monooxygenase, was investigated under steady-state and rapid reaction conditions using primary and solvent kinetic isotope effects, substrate analogs, pH and solvent viscosity effe...

Optimization of Direct Lysine Decarboxylase Biotransformation for Cadaverine Production with Whole-Cell Biocatalysts at High Lysine Concentration.

J. Microbiol. Biotechnol. 25 , 1108-13, (2015)

Cadaverine (1,5-diaminopentane) is an important industrial chemical with a wide range of applications. Although there have been many efforts to produce cadaverine through fermentation, there are not many reports of the direct cadaverine production from lysine...

Toward anticancer immunotherapeutics: well-defined polymer-antibody conjugates for selective dendritic cell targeting.

Macromol. Biosci. 14(10) , 1444-57, (2014)

This paper describes the synthesis of semitelechelic maleimide-modified N-(2-hydroxypropyl)methacrylamid) (HPMA) based polymers of narrow dispersity that can be conjugated e.g. to anti-DEC-205 antibodies affording "star-like" topologies (one antibody decorate...

Polyamines in conventional and organic vegetables exposed to exogenous ethylene.

Food Chem. 188 , 218-24, (2015)

Relationships between endogenous levels of polyamines by thin layer chromatography (TLC) and gas chromatography (GC), nitrate and response to the application of ethylene were established between organic and conventional vegetables (broccoli, collard greens, c...

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.

Nature 457(7231) , 910-4, (2009)

Multiple, complex molecular events characterize cancer development and progression. Deciphering the molecular networks that distinguish organ-confined disease from metastatic disease may lead to the identification of critical biomarkers for cancer invasion an...

RESOLFT nanoscopy with photoswitchable organic fluorophores.

Sci. Rep. 5 , 17804, (2015)

Far-field optical nanoscopy has been widely used to image small objects with sub-diffraction-limit spatial resolution. Particularly, reversible saturable optical fluorescence transition (RESOLFT) nanoscopy with photoswitchable fluorescent proteins is a powerf...

Improving the serum D-xylose test for the identification of patients with small intestinal malabsorption.

J. Clin. Gastroenterol. 33(1) , 36-40, (2001)

D-Xylose absorption testing is a simple, low-cost method of screening for small intestinal malabsorption. The optimum method to measure D-xylose absorption (serum vs. urine testing) is uncertain.We present a method of improving the accuracy of D-xylose testin...

An Extended-gate Type Organic FET Based Biosensor for Detecting Biogenic Amines in Aqueous Solution.

Anal. Sci. 31 , 721-4, (2015)

This study is the first to report on the detection of biogenic amines in an aqueous solution using an organic field-effect transistor (OFET) device with an extended gate electrode modified with a layer of diamine oxidase and a horseradish peroxidase osmium-re...

Metabolomics of adherent mammalian cells by capillary electrophoresis-mass spectrometry: HT-29 cells as case study.

J. Pharm. Biomed. Anal. 110 , 83-92, (2015)

In this work, the optimization of an effective protocol for cell metabolomics is described with special emphasis in the sample preparation and subsequent analysis of intracellular metabolites from adherent mammalian cells by capillary electrophoresis-mass spe...