D(-)-对羟基苯甘氨酸
D(-)-对羟基苯甘氨酸结构式
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常用名 | D(-)-对羟基苯甘氨酸 | 英文名 | (D)-(-)-α-4-hydroxyphenyl glycine |
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| CAS号 | 22818-40-2 | 分子量 | 167.162 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 365.8±32.0 °C at 760 mmHg | |
| 分子式 | C8H9NO3 | 熔点 | 240 °C (dec.)(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 175.0±25.1 °C |
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Role of glucose metabolism in the recovery of postischemic LV mechanical function: effects of insulin and other metabolic modulators.
Am. J. Physiol. Heart Circ. Physiol. 294(6) , H2576-86, (2008) The role of proton (H+) production from glucose metabolism in the recovery of myocardial function during postischemic reperfusion and its alteration by insulin and other metabolic modulators were examined. Rat hearts were perfused in vitro with Krebs-Henselei... |
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The enduracidin biosynthetic gene cluster from Streptomyces fungicidicus.
Microbiology 152(Pt 10) , 2969-83, (2006) The biosynthetic gene cluster for the 17 aa peptide antibiotic enduracidin has been cloned and sequenced from Streptomyces fungicidicus ATCC 21013. The 84 kb gene cluster contains 25 ORFs and is located within a 116 kb genetic locus that was fully sequenced. ... |
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Cardiac lipoprotein lipase activity in the hypertrophied heart may be regulated by fatty acid flux.
Biochim. Biophys. Acta 1821(4) , 627-36, (2012) Cardiac hypertrophy is characterised by an imbalance between lipid uptake and fatty acid β-oxidation leading to an accumulation of lipids, particularly triacylglycerol (TAG). It is unclear whether uptake mechanisms such as lipoprotein lipase (LPL) can be atte... |
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Carnitine palmitoyl transferase-I inhibition is not associated with cardiac hypertrophy in rats fed a high-fat diet.
Clin. Exp. Pharmacol. Physiol. 34(1-2) , 113-9, (2007) 1. Cardiac lipotoxicity is characterized by hypertrophy and contractile dysfunction and can be triggered by impaired mitochondrial fatty acid oxidation and lipid accumulation. The present study investigated the effect of dietary fatty acid intake alone and in... |
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Dissociation between metabolic and efficiency effects of perhexiline in normoxic rat myocardium.
J. Cardiovasc. Pharmacol. 46(6) , 849-55, (2005) The antianginal agent perhexiline inhibits rat cardiac carnitine palmitoyltransferase-1 (CPT-1) and CPT-2, key enzymes for mitochondrial transport of long-chain fatty acids. We tested the hypothesis that perhexiline, in therapeutic concentrations (2 microM), ... |
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Sequential activation of caspases and synergistic beta-cell cytotoxicity by palmitate and anti-Fas antibodies.
Life Sci. 79(13) , 1312-6, (2006) To assess the mechanism of beta-cell lipotoxicity in comparison with Fas-mediated cell death, we used a mouse beta-cell clone stably transfected with human Fas. Palmitate induced beta-cell death in correlation with medium glucose levels between 5 and 20 mmol/... |
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Identification and characterization of NocR as a positive transcriptional regulator of the beta-lactam nocardicin A in Nocardia uniformis.
J. Bacteriol. 191(3) , 1066-77, (2009) Nocardicin A is a monocyclic beta-lactam isolated from the actinomycete Nocardia uniformis, which shows moderate activity against a broad spectrum of gram-negative bacteria. Within the biosynthetic gene cluster of nocardicin A, nocR encodes a 583-amino-acid p... |
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4-Hydroxyphenylglycine biosynthesis in Herpetosiphon aurantiacus: a case of gene duplication and catalytic divergence.
Arch. Microbiol. 194(6) , 557-66, (2012) The nonproteinogenic amino acid 4-hydroxyphenylglycine (HPG) arises from the diversion of the tyrosine degradation pathway into secondary metabolism, and its biosynthesis requires a set of three enzymes. The gene cassette for HPG biosynthesis is widely spread... |
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Efficient biocatalytic production of D-4-hydroxyphenylglycine by whole cells of recombinant Ralstonia pickettii.
Folia Microbiol. (Praha) 54(6) , 509-15, (2009) The first establishment of a homologous expression system in the host Ralstonia pickettii CGMCC1596 using the compatible broad-host-range plasmid pWB5 is described. When whole cells of the recombinant strain R. pickettii MMYY01 (CGMCC1596/pYY05) were used as ... |
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Reducing the burden of ischemia reperfusion: editorial to: "Effect of Chronic CPT-1 Inhibition on Myocardial Ischemia-Reperfusion Injury (I/R) in a Model of Diet-Induced Obesity" by G. Maarman et al.
Cardiovasc. Drugs Ther. 26(3) , 193-4, (2012)
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