N-环己基甲酰胺结构式
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常用名 | N-环己基甲酰胺 | 英文名 | Formamide,N-cyclohexyl- |
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| CAS号 | 766-93-8 | 分子量 | 127.18400 | |
| 密度 | 0.96 g/cm3 | 沸点 | 113 °C700 mm Hg(lit.) | |
| 分子式 | C7H13NO | 熔点 | 36-41 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | >230 °F | |
| 符号 |
GHS05, GHS07 |
信号词 | Danger |
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Discovery of a novel enzyme, isonitrile hydratase, involved in nitrogen-carbon triple bond cleavage.
J. Biol. Chem. 276(26) , 23480-5, (2001) Isonitrile containing an N triple bond C triple bond was degraded by microorganism sp. N19-2, which was isolated from soil through a 2-month acclimatization culture in the presence of this compound. The isonitrile-degrading microorganism was identified as Pse... |
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A Raman spectroscopic characterization of bonding in the complex of horse liver alcohol dehydrogenase with NADH and N-cyclohexylformamide.
Biochemistry 37(40) , 14267-78, (1998) The binding of N-cyclohexylformamide (CXF) to the complex of horse liver alcohol dehydrogenase with NADH mimics that of the Michaelis complex for aldehyde reduction catalyzed by the enzyme. The Raman spectra of bound CXF and its 13C- and 15N-substituted deriv... |
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Crystal structures of mouse class II alcohol dehydrogenase reveal determinants of substrate specificity and catalytic efficiency.
J. Mol. Biol. 302(2) , 441-53, (2000) The structure of mouse class II alcohol dehydrogenase (ADH2) has been determined in a binary complex with the coenzyme NADH and in a ternary complex with both NADH and the inhibitor N-cyclohexylformamide to 2.2 A and 2.1 A resolution, respectively. The ADH2 d... |
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Binding of formamides to liver alcohol dehydrogenase.
Biochemistry 36(12) , 3522-7, (1997) Amides are analogs of aldehydes and potent inhibitors of liver alcohol dehydrogenases. They can be used for structural studies and for inhibiting the metabolism of alcohols that form toxic products. We studied N-alkyl amides that bind to the enzyme-NADH compl... |
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Uncompetitive inhibitors of alcohol dehydrogenases.
Adv. Exp. Med. Biol. 463 , 295-303, (1999)
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Selenium-containing heterocycles from isoselenocyanates: synthesis of 2-methylidene-1, 3-selenazolidine derivatives. Sommen GL, et al.
Tetrahedron 62(14) , 3344-3354, (2006)
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