盐酸阿糖胞苷
盐酸阿糖胞苷结构式
|
常用名 | 盐酸阿糖胞苷 | 英文名 | Cytarabine hydrochloride |
|---|---|---|---|---|
| CAS号 | 69-74-9 | 分子量 | 279.678 | |
| 密度 | N/A | 沸点 | 545.7ºC at 760 mmHg | |
| 分子式 | C9H14ClN3O5 | 熔点 | 197-198 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 283.8ºC | |
| 符号 |
GHS07, GHS08 |
信号词 | Warning |
|
An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease.
EMBO Mol. Med. 7(2) , 175-89, (2015) The β-site amyloid precursor protein cleaving enzyme-1 (BACE1), an essential protease for the generation of amyloid-β (Aβ) peptide, is a major drug target for Alzheimer's disease (AD). However, there is a concern that inhibiting BACE1 could also affect severa... |
|
|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ... |
|
|
Gingival pain: an unusual side effect of ziprasidone.
BMJ Case Rep. 2013 , doi:10.1136/bcr-2012-007577, (2013) The patient is a 52-year-old man with schizophrenia who developed severe, unremitting gingival pain after his ziprasidone dosage was increased from 80 to 120 mg. His physical examination and laboratory findings were unremarkable. He did not have any extra-pyr... |
|
|
Breakthrough Fusarium solani infection in a patient with acute myeloid leukemia receiving posaconazole prophylaxis.
Ann. Hematol. 93(6) , 1079-81, (2014)
|
|
|
The DNA damage response induces antigen presenting cell-like functions in fibroblasts.
Eur. J. Immunol. 44(4) , 1108-18, (2014) The DNA damage response (DDR) alerts the immune system to the danger posed by DNA damage through the induction of damage-associated molecular pattern molecules, chemokines, and ligands for activating immune receptors such as lymphocyte function-associated ant... |
|
|
Final report of phase II study of sorafenib, cytarabine and idarubicin for initial therapy in younger patients with acute myeloid leukemia.
Leukemia 28(7) , 1543-5, (2014)
|
|
|
Confirmation of the mantle-cell lymphoma International Prognostic Index in randomized trials of the European Mantle-Cell Lymphoma Network.
J. Clin. Oncol. 32(13) , 1338-46, (2014) Mantle-cell lymphoma (MCL) is a distinct B-cell lymphoma associated with poor outcome. In 2008, the MCL International Prognostic Index (MIPI) was developed as the first prognostic stratification tool specifically directed to patients with MCL. External valida... |
|
|
Augmented Berlin-Frankfurt-Münster therapy in adolescents and young adults (AYAs) with acute lymphoblastic leukemia (ALL).
Cancer 120(23) , 3660-8, (2014) Various trials have reported improved outcomes for adolescents and young adults (AYAs) with acute lymphoblastic leukemia (ALL) who received treatment with pediatric-based regimens. Those reports prompted the current investigation of the pediatric augmented Be... |
|
|
Sixteenth biannual report of the Cochrane Haematological Malignancies Group: focus on Non-Hodgkin's lymphoma.
J. Natl. Cancer Inst. 106(8) , doi:10.1093/jnci/dju170, (2014) This sixteenth biannual report of the Cochrane Haematological Malignancies Group highlights recently published randomized controlled trials (RCTs) in the field of hemato-oncology, with special focus on non-Hodgkin's lymphoma. The report covers the publication... |
|
|
Burkitt-like post-transplant lymphoproliferative disorder (PTLD) presenting with breast mass in a renal transplant recipient: a report of a rare case.
Ann. Hematol. 93(12) , 2083-5, (2014)
|