二氟甲基苯基砜结构式
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常用名 | 二氟甲基苯基砜 | 英文名 | [(Difluoromethyl)sulfonyl]benzene |
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| CAS号 | 1535-65-5 | 分子量 | 192.183 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 289.5±40.0 °C at 760 mmHg | |
| 分子式 | C7H6F2O2S | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 128.9±27.3 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Nucleophilic fluoroalkylation of alpha,beta-enones, arynes, and activated alkynes with fluorinated sulfones: probing the hard/soft nature of fluorinated carbanions.
J. Org. Chem. 15th ed., 73 , 5699-5713, (2008) We have successfully accomplished the nucleophilic fluoroalkylation of alpha,beta-enones, arynes, and activated alkynes with fluorinated sulfones. It was found that for acylic alpha,beta-enones, although the reaction medium and the structure of the enones can... |
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Preparation of tri- and difluoromethylsilanes via an unusual magnesium metal-mediated reductive tri- and difluoromethylation of chlorosilanes using tri- and difluoromethyl sulfides, sulfoxides, and sulfones.
J. Org. Chem. 11th ed., 68 , 4457-4463, (2003) A new and efficient method for the preparation of tri- and difluoromethylsilanes using magnesium metal-mediated reductive tri- and difluoromethylation of chlorosilanes is reported using tri- and difluoromethyl sulfides, sulfoxides, and sulfones. The byproduct... |
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Facile synthesis of chiral alpha-difluoromethyl amines from N-(tert-butylsulfinyl)aldimines.
Angew. Chem. Int. Ed. Engl. 36th ed., 44 , 5882-5886, (2005)
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Nucleophilic difluoromethylation of primary alkyl halides using difluoromethyl phenyl sulfone as a difluoromethyl anion equivalent.
Org. Lett. 23th ed., 6 , 4315-4317, (2004) A facile and efficient nucleophilic difluoromethylation of primary alkyl halides has been disclosed through a novel nucleophilic substitution-reductive desulfonylation strategy, using difluoromethyl phenyl sulfone as a difluoromethyl anion ("CF(2)H(-)") equiv... |
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Stereoselective synthesis of di- and monofluoromethylated vicinal ethylenediamines with di- and monofluoromethyl sulfones.
J. Org. Chem. 8th ed., 72 , 3119-3121, (2007) The diastereoselective nucleophilic (phenylsulfonyl)difluoromethylation and (phenylsulfonyl)monofluoromethylation of alpha-amino N-tert-butanesulfinimines (3) by using PhSO2CF2H and PhSO2CH2F reagents gave products 4 or 5 in high yields (73-99%) and with exce... |
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A remarkably efficient fluoroalkylation of cyclic sulfates and sulfamidates with PhSO2CF2H: facile entry into beta-difluoromethylated or beta-difluoromethylenated alcohols and amines.
Angew. Chem. Int. Ed. Engl. 5th ed., 46 , 786-789, (2007)
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Difluoromethyl phenyl sulfone, a difluoromethylidene equivalent: use in the synthesis of 1,1-difluoro-1-alkenes.
Angew. Chem. Int. Ed. Engl. 39th ed., 43 , 5203-5206, (2004)
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Difluoromethyl phenyl sulfone as a selective difluoromethylene dianion equivalent: one-pot stereoselective synthesis of anti-2,2-difluoropropane-1,3-diols.
Angew. Chem. Int. Ed. Engl. 42th ed., 42 , 5216-5219, (2003)
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Convenient synthesis of difluoromethyl alcohols from both enolizable and non-enolizable carbonyl compounds with difluoromethyl phenyl sulfone Prakash, G. K. S.; et al.
European J. Org. Chem. 11 , 2218-2223, (2005)
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