羟苯基丙酸 N-羟基琥珀酰亚胺酯结构式
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常用名 | 羟苯基丙酸 N-羟基琥珀酰亚胺酯 | 英文名 | Benzenepropanoic acid,4-hydroxy-, 2,5-dioxo-1-pyrrolidinyl ester |
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| CAS号 | 34071-95-9 | 分子量 | 263.24600 | |
| 密度 | 1.4 g/cm3 | 沸点 | 448.8ºC | |
| 分子式 | C13H13NO5 | 熔点 | 132-133ºC(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 225.2ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Tumor-targeted delivery of paclitaxel using low density lipoprotein-mimetic solid lipid nanoparticles.
Mol. Pharm. 12(4) , 1230-41, (2015) Water-insoluble anticancer drugs, including paclitaxel, present severe clinical side effects when administered to patients, primarily associated with the toxicity of reagents used to solubilize the drugs. In efforts to develop alternative formulations of wate... |
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Diabody Pretargeting with Click Chemistry In Vivo.
J. Nucl. Med. 56 , 1422-8, (2015) Radioimmunotherapy and nuclear imaging (immuno-PET/SPECT) of cancer with radiometal-labeled antibody fragments or peptides is hampered by low tumor-to-kidney ratios because of high renal radiometal retention. Therefore, we developed and evaluated a pretargeti... |
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Appendix: Preparation of N-succinimidyl 3-(4-hydroxyphenyl)propionate.
Biochem. J. 133 , 538, (1973)
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The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent.
Biochem. J. 133 , 529-539, (1973) 1. A new method is described for labelling proteins to high specific radioactivities with (125)I. The protein is treated with a (125)I-labelled acylating agent, iodinated 3-(4-hydroxyphenyl)propionic acid N-hydroxysuccinimide ester, which reacts with free ami... |
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Radioiodination and biodistribution of quantum dots using Bolton-Hunter reagent.
Appl. Radiat. Isot. 69 , 56-62, (2011) In this study, the radioiodination and biodistribution of quantum dots (QDs) using Bolton-Hunter reagent were investigated. Radioiodination yield was 33.4 ± 2.0%. Fluorescent intensity of radioiodinated QDs decreased to 75.4% of the maximum prior to radioiodi... |
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A comparison of two procedures for labelling the surface of the hydatid disease organism, Echinococcus granulosus, with 125I.
J. Helminthol. 61 , 47-52, (1987) Living, intact protoscoleces of the British horse and sheep strains of Echinococcus granulosus were subjected to surface radioiodination procedures using 125I and Iodogen and 125I-Bolton Hunter reagent. Subsequent combined electron microscopy and autoradiogra... |
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A simple method for the radioactive iodination of CD4 molecules.
J. Immunol. Methods 129 , 105-109, (1990) A method for the vectorial radioiodination of CD4 and other membrane proteins having few or no tyrosine residues in the extracytoplasmic domains is described. Incubation of the cells with sulfosuccinimidyl (hydroxyphenyl) propionate (sulfo-SHPP), a water-solu... |
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Trans-cyclooctene tag with improved properties for tumor pretargeting with the diels-alder reaction.
Mol. Pharm. 11(9) , 3090-6, (2014) Radioimmunotherapy (RIT) of solid tumors is hampered by low tumor-to-nontumor (T/NT) ratios of the radiolabeled monoclonal antibodies resulting in low tumor doses in patients. Pretargeting technologies can improve the effectiveness of RIT in cancer therapy by... |
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Purification and radiolabeling of human C1q.
J. Immunol. 127(2) , 648-53, (1981) A new procedure for isolating human C1q from serum or plasma is described. The method, that is highly selective, rapid and involves minimal handling, yields fully active, immunoglobulin-free unaggregated C1q. Several different methods of radiolabeling C1q are... |
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An evaluation of different methods for labelling the surface of the filarial nematode Brugia pahangi with 125iodine.
Mol. Biochem. Parasitol. 15(3) , 295-304, (1985) The specificity of a range of 125I labelling techniques (Chloramine T, Iodogen, Bolton and Hunter reagent, lactoperoxidase and iodosulfanilic acid) to the surface of the filarial nematode Brugia pahangi was evaluated by autoradiography of sections of labelled... |