一水硫酸阿托品

Pulm. Pharmacol. Ther. 28(2) , 114-21, (2014)

This study characterised the in vitro and in vivo profiles of two novel long-acting muscarinic antagonists, aclidinium bromide and glycopyrronium bromide, using tiotropium bromide and ipratropium bromide as comparators. All four antagonists had high affinity ...

Pharm. Biol. 53(4) , 594-9, (2015)

1,8-Cineole, a terpene, characterized as a major constituent occurring in the essential oils of several aromatic plants. It is widely used in pharmaceutical industry, as a food additive and for culinary purposes.This study investigates the inhibitory effect o...

J. Cardiovasc. Pharmacol. 65(1) , 62-71, (2015)

Previous studies have found that Danhong injection (DHI), an extensively used herbal extract preparation in China, might be a powerful vasodilator. The aims of this study were to determine the vascular activity of DHI and its effects on arteries of different ...

Pharmazie 70(3) , 183-92, (2015)

DA-9701, a new prokinetic agent for the treatment of functional dyspepsia, is formulated with Pharbitis semen and Corydalis tuber. This study wasconducted to determine the pharmacological action of DA-9701 and to identify the receptors involved in DA-9701 -in...

J. Am. Coll. Surg. 220(5) , 921-33, (2015)

Background Recurrent laryngeal nerve palsy (RLNP) and hypoparathyroidism are complications of thyroid surgery. The convalescence can depend on several factors (ie, pain, fatigue, nausea, and vomiting). Supplemental oxygen improves inflammatory and immune func...

Neurochem. Res. 39(8) , 1477-83, (2014)

The nociceptin/orphanin FQ peptide (NOP) receptor and its endogenous ligand plays role in several physiologic functions of the central nervous system, including pain, locomotion, anxiety and depression, reward and drug addiction, learning and memory. Previous...

J. Neurosci. 35(2) , 761-75, (2015)

The modulation of gamma power (25-90 Hz) is associated with attention and has been observed across species and brain areas. However, mechanisms that control these modulations are poorly understood. The midbrain spatial attention network in birds generates hig...

Neuropharmacology 89 , 11-8, (2014)

Exposure to nerve agents can cause brain damage due to prolonged seizure activity, producing long-term behavioral deficits. We have previously shown that LY293558, a GluK1/AMPA receptor antagonist, is a very effective anticonvulsant and neuroprotectant agains...

J. Neurosci. 34(30) , 10122-33, (2014)

Visual responsiveness of cortical neurons changes depending on the brain state. Neural circuit mechanism underlying this change is unclear. By applying the method of in vivo two-photon functional calcium imaging to transgenic rats in which GABAergic neurons e...

PLoS ONE 9(8) , e105996, (2014)

Visual sensory impairments are common in Mental Deficiency (MD) and Autism Spectrum Disorder (ASD). These defects are linked to cerebral dysfunction in the visual cortical area characterized by the deregulation of axon growth/guidance and dendrite spine immat...