阿托品； 颠茄碱结构式
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常用名 | 阿托品； 颠茄碱 | 英文名 | Atropine |
|---|---|---|---|---|
| CAS号 | 51-55-8 | 分子量 | 289.369 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 429.8±45.0 °C at 760 mmHg | |
| 分子式 | C17H23NO3 | 熔点 | 115-118 °C | |
| MSDS | 中文版 美版 | 闪点 | 213.7±28.7 °C | |
| 符号 |
GHS02, GHS06 |
信号词 | Danger |
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Enhanced Retinal Ganglion Cell Survival in Glaucoma by Hypoxic Postconditioning After Disease Onset.
Neurotherapeutics 12(2) , 502-14, (2015) The neuroprotective efficacy of adaptive epigenetics, wherein beneficial gene expression changes are induced by nonharmful "conditioning" stimuli, is now well established in several acute, preclinical central nervous system injury models. Recently, in a mouse... |
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Receptor mediated disruption of retinal pigment epithelium function in acute glycated-albumin exposure.
Exp. Eye Res. 137 , 50-6, (2015) Diabetic macular edema (DME) is a major cause of visual impairment. Although DME is generally believed to be a microvascular disease, dysfunction of the retinal pigment epithelium (RPE) can also contribute to its development. Advanced glycation end-products (... |
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Role of Telokin in Regulating Murine Gastric Fundus Smooth Muscle Tension.
PLoS ONE 10 , e0134876, (2015) Telokin phosphorylation by cyclic GMP-dependent protein kinase facilitates smooth muscle relaxation. In this study we examined the relaxation of gastric fundus smooth muscles from basal tone, or pre-contracted with KCl or carbachol (CCh), and the phosphorylat... |
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The novel protein kinase C epsilon isoform modulates acetylcholine release in the rat neuromuscular junction.
Mol. Brain 8 , 80, (2015) Various protein kinase C (PKC) isoforms contribute to the phosphorylating activity that modulates neurotransmitter release. In previous studies we showed that nPKCε is confined in the presynaptic site of the neuromuscular junction and its presynaptic function... |
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Generation and characterization of a murine model of Bietti crystalline dystrophy.
Invest. Ophthalmol. Vis. Sci. 55(9) , 5572-81, (2014) Bietti crystalline dystrophy (BCD) is a rare, autosomal recessive, progressive, degenerative eye disease caused by mutations in the CYP4V2 gene, for which no treatments are currently available. Cyp4v3 is the murine ortholog to CYP4V2, and to better understand... |
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Action of anti-M₃muscarinic acetylcholine receptor IgG of primary Sjögren's syndrome on the enzymatic antioxidant system in rat submandibular gland.
J. Oral. Pathol. Med. 44 , 876-83, (2015) We demonstrate that serum immunoglobulin G (IgG) directed against glandular M3 muscarinic acetylcholine receptors (M₃mAChR) and pilocarpine triggers the increment of superoxide dismutase (SOD) and catalase (CAT) and the production of nitric oxide (NO) and pro... |
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Chloroform extract of underground parts of Ferula heuffelii: secondary metabolites and spasmolytic activity.
Chem. Biodivers. 11(9) , 1417-27, (2014) Plants from the genus Ferula L. (Apiaceae) were used for various purposes in traditional medicine of different nations throughout the history. Ferula heuffelii Griseb. ex Heuffel is a perennial species endemic for Balkan peninsula. Ten compounds which belong ... |
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Preliminary report: modulation of parasympathetic nervous system tone influences oesophageal pain hypersensitivity.
Gut 64(4) , 611-7, (2015) Autonomic nervous system dysfunction has been implicated in visceral hypersensitivity. However, the specific contribution of the parasympathetic nervous system (PNS) is unclear. We aimed to determine whether physiological and pharmacological manipulation of p... |
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Tropane and ergot alkaloids in grain-based products for infants and young children in the Netherlands in 2011-2014.
Food. Addit. Contam. Part. B. Surveill. 8 , 284-90, (2015) An LC-MS/MS multi-method was developed to simultaneously quantify ergot alkaloids (EAs) and tropane alkaloids (TAs) in 113 cereal-based food for infants and young children. To assess yearly variation, samples were collected in 2011, 2012 and 2014. EAs were de... |
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Fasting stimulates 2-AG biosynthesis in the small intestine: role of cholinergic pathways.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 309 , R805-13, (2015) The endocannabinoids are lipid-derived signaling molecules that control feeding and energy balance by activating CB1-type cannabinoid receptors in the brain and peripheral tissues. Previous studies have shown that oral exposure to dietary fat stimulates endoc... |