己二腈
一般危化品
己二腈结构式
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常用名 | 己二腈 | 英文名 | Adiponitrile |
|---|---|---|---|---|
| CAS号 | 111-69-3 | 分子量 | 108.141 | |
| 密度 | 0.9±0.1 g/cm3 | 沸点 | 296.1±13.0 °C at 760 mmHg | |
| 分子式 | C6H8N2 | 熔点 | 1-3 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 149.0±13.7 °C | |
| 符号 |
GHS06 |
信号词 | Danger |
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An amino acid at position 142 in nitrilase from Rhodococcus rhodochrous ATCC 33278 determines the substrate specificity for aliphatic and aromatic nitriles.
Biochem. J. 415 , 401-7, (2008) Nitrilase from Rhodococcus rhodochrous ATCC 33278 hydrolyses both aliphatic and aromatic nitriles. Replacing Tyr-142 in the wild-type enzyme with the aromatic amino acid phenylalanine did not alter specificity for either substrate. However, the mutants contai... |
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Variable interaction network based variable selection for multivariate calibration.
Anal. Chim. Acta 599(1) , 24-35, (2007) Multivariate calibration problems often involve the identification of a meaningful subset of variables, from a vast number of variables for better prediction of output variables. A new graph theoretic method based on partial correlations (variable interaction... |
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Evaluation of the teratogenic potential of three aliphatic nitriles in the rat.
Fundam. Appl. Toxicol. 7(1) , 33-40, (1986) Acetonitrile (ACN), adiponitrile (ADN), and propionitrile (PN), were evaluated for embryotoxic and teratogenic potential in rats. Mated Sprague-Dawley rats were administered one of the three nitriles by gavage on gestation Days 6-19, inclusive. Daily dosage l... |
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Development of wet environment TEM (wet-ETEM) for in situ studies of liquid-catalyst reactions on the nanoscale.
Microsc. Microanal. 8(1) , 21-8, (2002) We present the development of in situ wet environmental transmission electron microscopy (wet-ETEM) for direct probing of controlled liquid-catalyst reactions at operating temperatures on the nanoscale. The first nanoscale imaging and electron diffraction of ... |
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The effects of fasting on the acute oral toxicity of nine chemicals in the rat.
J. Appl. Toxicol. 4(6) , 320-5, (1984) Nine chemicals, with a range from extremely to slightly toxic, were used to measure the oral LD50 in both fasted (24-h) and non-fasted rats. Each chemical was tested as a solution or suspension in corn oil, responses within 14 days post-treatment were evaluat... |
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Electrochemical synthesis of adiponitrile from the renewable raw material glutamic acid.
ChemSusChem 5(4) , 617-20, (2012) Current affairs: Adiponitrile, used to produce nylon 6.6, is prepared from the renewable compound glutamic acid by an electrochemical route, involving electro-oxidative decarboxylation and Kolbe coupling reactions. The new route is an example of the use of gl... |
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13-week inhalation toxicity study and fertility assessment in rats exposed to atmospheres containing adiponitrile.
J. Toxicol. Environ. Health A 30(3) , 199-207, (1990) Adiponitrile is an aliphatic dinitrile that is used as an intermediate in the synthesis of hexamethylenediamine. In order to asses potential health effects associated with industrial exposure, rats were exposed 6 h/d, 5 d/wk for 4 or 13 wk to atmospheres cont... |
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Application of high-performance liquid chromatography to the study of the biological transformation of adiponitrile by nitrile hydratase and amidase.
Analyst 116(12) , 1381-3, (1991) A procedure for the assay of nitrile hydratase and amidase activities by high-performance liquid chromatography is described. The method can be used to assay the intermediate compounds resulting from the hydrolysis of adiponitrile to adipic acid, and to deter... |
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Inhalation toxicity of adiponitrile in rats.
Toxicol. Appl. Pharmacol. 65(2) , 257-63, (1982)
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Application of high-performance liquid chromatography to the study of the biological transformation of adiponitrile.
J. Chromatogr. B, Biomed. Appl. 656(1) , 197-202, (1994) A procedure for the assay of nitrile hydratase and amidase activity by high-performance liquid chromatography is described. The method can be used to assay the intermediate compounds resulting from the hydrolysis of adiponitrile into adipic acid, and to deter... |