对氨基水杨酸
对氨基水杨酸结构式
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常用名 | 对氨基水杨酸 | 英文名 | 4-aminosalicylic acid |
|---|---|---|---|---|
| CAS号 | 65-49-6 | 分子量 | 153.135 | |
| 密度 | 1.5±0.1 g/cm3 | 沸点 | 380.8±32.0 °C at 760 mmHg | |
| 分子式 | C7H7NO3 | 熔点 | 135-145 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 184.1±25.1 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Synthesis of lysozyme-metallacarborane conjugates and the effect of boron cluster modification on protein structure and function.
ChemBioChem. 16(3) , 424-31, (2015) Two complementary methods, "in solution" and "in solid state", for the synthesis of lysozyme modified with metallacarborane (cobalt bis(dicarbollide), Co(C2 B9 H11 )2 (2-) ) were developed. As metallacarborane donors, oxonium adducts of cobalt bis(dicarbollid... |
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Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung.
Nature 528 , 127-31, (2015) Prevailing dogma holds that cell-cell communication through Notch ligands and receptors determines binary cell fate decisions during progenitor cell divisions, with differentiated lineages remaining fixed. Mucociliary clearance in mammalian respiratory airway... |
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Simple and accurate quantitative analysis of 20 anti-tuberculosis drugs in human plasma using liquid chromatography-electrospray ionization-tandem mass spectrometry.
J. Pharm. Biomed. Anal. 102 , 9-16, (2014) A simple and accurate liquid chromatography (LC)-tandem mass spectrometry (MS/MS) method for the quantitation of 20 anti-tuberculosis (anti-TB) drugs in human plasma, was developed as a tool for therapeutic drug monitoring. Two protein precipitation methods w... |
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Benzalkonium chloride induces subconjunctival fibrosis through the COX-2-modulated activation of a TGF-β1/Smad3 signaling pathway.
Invest. Ophthalmol. Vis. Sci. 55(12) , 8111-22, (2014) The purpose is to investigate the mechanism of subconjunctival fibrosis caused by benzalkonium chloride (BAC), which is the most common preservative in ophthalmic preparations.The left eyes of male Sprague-Dawley rats were topically treated with 0.01% BAC or ... |
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Chromatographic evaluation and QSAR optimization for benzoic acid analogues against carbonic anhydrase III.
J. Enzyme Inhib. Med. Chem. 30 , 420-9, (2015) An HPLC-size exclusion method was developed as an assay method to evaluate the binding of tested compounds with carbonic anhydrase III (CAIII) enzyme. Inhibition of CAIII by a group of benzoic acid analogues was characterized by vacancy (negative) peak intens... |
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Functional differentiation of human pluripotent stem cells on a chip.
Nature Methods 12 , 637-40, (2015) Microengineering human "organs-on-chips" remains an open challenge. Here, we describe a robust microfluidics-based approach for the differentiation of human pluripotent stem cells directly on a chip. Extrinsic signal modulation, achieved through optimal frequ... |
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Differential expression and therapeutic efficacy of microRNA-346 in diabetic nephropathy mice.
Exp. Ther. Med. 10 , 106-112, (2015) Diabetic nephropathy (DN) is a major cause of end-stage renal disease, in which the SMAD signaling pathway plays an important role. The aim of the present study was to identify differentially expressed microRNAs (miRNAs) during the progression of DN and to in... |
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Characterization of a Hormone-Responsive Organotypic Human Vaginal Tissue Model: Morphologic and Immunologic Effects.
Reprod. Sci. 22 , 980-90, (2015) Estrogen and progesterone regulate proliferation and differentiation of epithelial cells in the female genital tract. We investigated the effects of these hormones on reconstructed human organotypic vaginal epithelial tissue models (EpiVaginal). We ascertaine... |
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Adsorption of phenolic compounds from aqueous solution using salicylic acid type adsorbent.
J. Hazard. Mater. 201-202 , 74-81, (2012) In this study, 5-aminosalicylic acid (5-ASA) was successfully grafted onto the poly(glycidyl methacrylate) (PGMA) macromolecular chains of PGMA/SiO(2) to obtain adsorbent ASA-PGMA/SiO(2). The adsorption properties of ASA-PGMA/SiO(2) for phenolic compounds wer... |
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New NCI-N87-derived human gastric epithelial line after human telomerase catalytic subunit over-expression.
World J. Gastroenterol. 21 , 6526-42, (2015) To establish a cellular model correctly mimicking the gastric epithelium to overcome the limitation in the study of Helicobacter pylori (H. pylori) infection.Aiming to overcome this limitation, clones of the heterogenic cancer-derived NCI-N87 cell line were i... |