3,5-二氯苯胺

一般危化品
3,5-二氯苯胺结构式
3,5-二氯苯胺结构式
常用名 3,5-二氯苯胺 英文名 3,5-Dichloroaniline
CAS号 626-43-7 分子量 162.017
密度 1.4±0.1 g/cm3 沸点 260.6±0.0 °C at 760 mmHg
分子式 C6H5Cl2N 熔点 49 °C
MSDS 中文版 美版 闪点 118.3±21.8 °C
符号 GHS06 GHS08 GHS09
GHS06, GHS08, GHS09
信号词 Danger

Exploring the active conformation of cyclohexane carboxylate positive allosteric modulators of the type 4 metabotropic glutamate receptor.

ChemMedChem 9(12) , 2685-98, (2014)

The active conformation of a family of metabotropic glutamate receptor subtype 4 (mGlu4 ) positive allosteric modulators (PAMs) with the cyclohexane 1,2-dicarboxylic scaffold present in cis-2-(3,5-dichlorophenylcarbamoyl)cyclohexanecarboxylic acid (VU0155041)...

Aquatic multi-species acute toxicity of (chlorinated) anilines: experimental versus predicted data.

Chemosphere 81(2) , 177-86, (2010)

Aquatic toxicity information is essential in environmental risk assessment to determine the potential hazards and risks of new and existing chemicals. Prediction and modelling techniques, such as quantitative structure activity relationships (QSAR) and specie...

LuxCDABE--transformed constitutively bioluminescent Escherichia coli for toxicity screening: comparison with naturally luminous Vibrio fischeri.

Sensors 11 , 7865-78, (2011)

We show that in vitro toxicity assay based on inhibition of the bioluminescence of recombinant Escherichia coli encoding thermostable luciferase from Photorhabdus luminescens is a versatile alternative to Vibrio fischeri Microtox™ test. Performance of two lux...

Effect of chemical form, route of administration and vehicle on 3,5-dichloroaniline-induced nephrotoxicity in the Fischer 344 rat.

J. Appl. Toxicol. 14(6) , 417-22, (1994)

Chloroanilines are widely used chemical intermediates for the manufacture of dyes, agricultural chemicals and industrial compounds. Nephrotoxicity occurs as one toxicity following intraperitoneal (i.p.) administration of chloroaniline hydrochlorides to rats. ...

Inclusion of the fungicide chlozolinate in a multiresidue method.

J. Chromatogr. A. 858(1) , 123-31, (1999)

A multiresidue GC method for the monitoring of electron-capturing compounds has been validated for the fungicide chlozolinate in the four crops with uses to be supported during re-evaluation procedures within the European Union. The method was also tested for...

Residue analysis of imazapyr and chlozolinate in water using sunlight.

Bull. Environ. Contam. Toxicol. 63(1) , 33-8, (1999)

Multiresidue determination of fungicides in wine.

Bull. Environ. Contam. Toxicol. 62(6) , 717-22, (1999)

Microbial biodegradation and toxicity of vinclozolin and its toxic metabolite 3,5-dichloroaniline.

J. Microbiol. Biotechnol. 18(2) , 343-9, (2008)

Vinclozolin, an endocrine disrupting chemical, is a chlorinated fungicide widely used to control fungal diseases. However, its metabolite 3,5-dichloroaniline is more toxic and persistent than the parent vinclozolin. For the biodegradation of vinclozolin, vinc...

Development and evaluation of an HPLC urinalysis screening test for occupational exposure to 3,4- and 3,5-dichloroanilines.

Int. J. Clin. Pharmacol. Ther. 40(1) , 41-6, (2002)

In order to develop a screening test to detect human occupational exposure to aromatic amines such as 3,4-dichloroaniline (3,4-DCA) and 3,5-dichloroaniline (3,5-DCA), we first investigated the urinary excretion of these highly toxic compounds in the rat. The ...

Enchytraeus crypticus as model species in soil ecotoxicology.

Chemosphere 87(11) , 1222-7, (2012)

Enchytraeids are ecologically relevant soil organisms, due to their activity in decomposition and bioturbation in many soil types worldwide. The enchytraeid reproduction test (ERT) guidelines ISO 16387 and OECD 220 are exclusive to the genus Enchytraeus and r...