2-羟基-5-氟嘧啶结构式
|
常用名 | 2-羟基-5-氟嘧啶 | 英文名 | 5-FLUORO-2-HYDROXYPYRIMIDINE |
|---|---|---|---|---|
| CAS号 | 2022-78-8 | 分子量 | 114.07800 | |
| 密度 | 1.46g/cm3 | 沸点 | N/A | |
| 分子式 | C4H3FN2O | 熔点 | 170-174ºC | |
| MSDS | 美版 | 闪点 | N/A | |
| 符号 |
GHS05, GHS07 |
信号词 | Danger |
|
Phase I clinical trial of 5-fluoro-pyrimidinone (5FP), an oral prodrug of 5-fluorouracil (5FU).
Invest. New Drugs 20(1) , 63-71, (2002) 5-Fluoro-Pyrimidinone (5FP) is an oral pro-drug of 5-Fluorouracil (5FU), and is converted to 5FU by hepatic aldehyde oxidase. Preclinically, 5FP demonstrated anti-tumor activity against colon 38 and P 388 leukemia models in mice. Using an accelerated titratio... |