三甲基氯硅烷

一般危化品
三甲基氯硅烷结构式
三甲基氯硅烷结构式
常用名 三甲基氯硅烷 英文名 Chlorotrimethylsilane
CAS号 75-77-4 分子量 108.642
密度 0.9±0.1 g/cm3 沸点 58.7±9.0 °C at 760 mmHg
分子式 C3H9ClSi 熔点 −40 °C(lit.)
MSDS 中文版 美版 闪点 -27.8±0.0 °C
符号 GHS02 GHS05 GHS06
GHS02, GHS05, GHS06
信号词 Danger

ALD1 Regulates Basal Immune Components and Early Inducible Defense Responses in Arabidopsis.

Mol. Plant Microbe Interact. 28(4) , 455-66, (2015)

Robust immunity requires basal defense machinery to mediate timely responses and feedback cycles to amplify defenses against potentially spreading infections. AGD2-LIKE DEFENSE RESPONSE PROTEIN 1 (ALD1) is needed for the accumulation of the plant defense sign...

Mechanistic Scrutiny Identifies a Kinetic Role for Cytochrome b5 Regulation of Human Cytochrome P450c17 (CYP17A1, P450 17A1).

PLoS ONE 10 , e0141252, (2015)

Cytochrome P450c17 (P450 17A1, CYP17A1) is a critical enzyme in the synthesis of androgens and is now a target enzyme for the treatment of prostate cancer. Cytochrome P450c17 can exhibit either one or two physiological enzymatic activities differentially regu...

Overcoming the equivalent-chain-length rule with pH-zone-refining countercurrent chromatography for the preparative separation of fatty acids.

Anal. Bioanal. Chem 407 , 5503-11, (2015)

Purification of individual fatty acids from vegetable oils by preparative liquid chromatography techniques such as countercurrent chromatography (CCC) is a challenging task due to the equivalent-chain-length (ECL) rule. It implies that one double bond equals ...

Free radical scavenging activity and comparative metabolic profiling of in vitro cultured and field grown Withania somnifera roots.

PLoS ONE 10(4) , e0123360, (2015)

Free radical scavenging activity (FRSA), total phenolic content (TPC), and total flavonoid content (TFC) of in vitro cultured and field grown Withania somnifera (Ashwagandha) roots were investigated. Withanolides analysis and comprehensive metabolic profiling...

S-equol Partially Restored Endothelial Nitric Oxide Production in Isoflavone-deficient Ovariectomized Rats.

J. Cardiovasc. Pharmacol. 65 , 500-7, (2015)

S-equol is known as an estrogenic substance, but its ability to restore vascular endothelial function is unknown. The aim of this study was to investigate the impact of S-equol on endothelial function and intimal thickening under isoflavone- and estrogen-defi...

Multiresidue method for the determination of pharmacologically active substances in egg and honey using a continuous solid-phase extraction system and gas chromatography-mass spectrometry.

Food Chem. 178 , 63-9, (2015)

A sensitive, selective, efficient gas chromatography-mass spectrometry method for the simultaneous determination of 22 pharmacologically active substances (antibacterials, nonsteroidal antiinflammatories, antiseptics, antiepileptics, lipid regulators, β-block...

Effect of surface functionality of silica nanoparticles on cellular uptake and cytotoxicity.

Mol. Pharm. 11(10) , 3642-55, (2014)

Mesoporous silica nanoparticles (MCM-41) with different surface chemistry were used as carrier system to study its influence on drug delivery and anticancer activity of curcumin (CUR). CUR was encapsulated in pristine MCM-41 (hydrophilic and negatively charge...

Serum and adipose tissue amino acid homeostasis in the metabolically healthy obese.

J. Proteome Res. 13(7) , 3455-66, (2014)

A subgroup of obese individuals, referred to as metabolically healthy obese (MHO), have preserved insulin sensitivity and a normal lipid profile despite being obese. The molecular basis for this improved cardiometabolic profile remains unclear. Our objective ...

Combination of direct infusion mass spectrometry and gas chromatography mass spectrometry for toxicometabolomic study of red blood cells and serum of mice Mus musculus after mercury exposure.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 985 , 75-84, (2015)

Although mercury (Hg) is an important environmental and occupational pollutant, its toxicological effects, especially in serum and red blood cells (RBCs), have been scarcely studied. A toxicometabolomics workflow based on high resolution mass spectrometry app...

Characterization of novel acyl coenzyme A dehydrogenases involved in bacterial steroid degradation.

J. Bacteriol. 197(8) , 1360-7, (2015)

The acyl coenzyme A (acyl-CoA) dehydrogenases (ACADs) FadE34 and CasC, encoded by the cholesterol and cholate gene clusters of Mycobacterium tuberculosis and Rhodococcus jostii RHA1, respectively, were successfully purified. Both enzymes differ from previousl...