乙腈结构式
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常用名 | 乙腈 | 英文名 | Acetonitrile |
|---|---|---|---|---|
| CAS号 | 75-05-8 | 分子量 | 41.052 | |
| 密度 | 0.7±0.1 g/cm3 | 沸点 | 81-82 ºC | |
| 分子式 | C2H3N | 熔点 | −45 °C | |
| MSDS | 中文版 美版 | 闪点 | 2 ºC | |
| 符号 |
GHS02, GHS07 |
信号词 | Danger |
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Neuroprotective effect of modified Chungsimyeolda-tang, a traditional Korean herbal formula, via autophagy induction in models of Parkinson's disease.
J. Ethnopharmacol. 159 , 93-101, (2014) Previous studies in our laboratory revealed the neuroprotective effect of modified Yeoldahanso-tang (MYH) in models of Parkinson׳s disease (PD). In this study, we investigated another traditional Korean herbal formula, modified Chungsimyeolda-tang (termed DG)... |
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Biomolecular imaging with a C60-SIMS/MALDI dual ion source hybrid mass spectrometer: instrumentation, matrix enhancement, and single cell analysis.
J. Am. Soc. Mass Spectrom. 25(11) , 1897-907, (2014) We describe a hybrid MALDI/C(60)-SIMS Q-TOF mass spectrometer and corresponding sample preparation protocols to image intact biomolecules and their fragments in mammalian spinal cord, individual invertebrate neurons, and cultured neuronal networks. A lateral ... |
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Itraconazole suppresses the growth of glioblastoma through induction of autophagy: involvement of abnormal cholesterol trafficking.
Autophagy 10(7) , 1241-55, (2014) Glioblastoma is one of the most aggressive human cancers with poor prognosis, and therefore a critical need exists for novel therapeutic strategies for management of glioblastoma patients. Itraconazole, a traditional antifungal drug, has been identified as a ... |
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Diclofenac toxicity in human intestine ex vivo is not related to the formation of intestinal metabolites.
Arch. Toxicol. 89(1) , 107-19, (2015) The use of diclofenac (DCF), a nonsteroidal anti-inflammatory drug, is associated with a high prevalence of gastrointestinal side effects. In vivo studies in rodents suggested that reactive metabolites of DCF produced by the liver or the intestine might be re... |
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Methionine oxidation accelerates the aggregation and enhances the neurotoxicity of the D178N variant of the human prion protein.
Biochim. Biophys. Acta 1842(12 Pt A) , 2345-56, (2014) The D178N mutation of the prion protein (PrP) results in the hereditary prion disease fatal familial insomnia (FFI). Little is known regarding the effects of methionine oxidation on the pathogenesis of D178N-associated FFI. In the present study, we found that... |
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Quantification of furanic derivatives in fortified wines by a highly sensitive and ultrafast analytical strategy based on digitally controlled microextraction by packed sorbent combined with ultrahigh pressure liquid chromatography.
J. Chromatogr. A. 1381 , 54-63, (2015) An improved, reliable and powerful analytical strategy based on digitally controlled microextraction by packed sorbent (MEPS) combined with ultrahigh pressure liquid chromatography (UHPLC) was validated for the simultaneous identification and quantification o... |
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Use of an enzyme-assisted method to improve protein extraction from olive leaves.
Food Chem. 169 , 28-33, (2014) The improvement of protein extraction from olive leaves using an enzyme-assisted protocol has been investigated. Using a cellulase enzyme (Celluclast® 1.5L), different parameters that affect the extraction process, such as the influence and amount of organic ... |
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Studies on the catalytic domains of multiple JmjC oxygenases using peptide substrates.
Epigenetics 9(12) , 1596-603, (2015) The JmjC-domain-containing 2-oxoglutarate-dependent oxygenases catalyze protein hydroxylation and N(ϵ)-methyllysine demethylation via hydroxylation. A subgroup of this family, the JmjC lysine demethylases (JmjC KDMs) are involved in histone modifications at m... |
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Fabrication of extended-release patient-tailored prednisolone tablets via fused deposition modelling (FDM) 3D printing.
Eur. J. Pharm. Sci. 68 , 11-7, (2015) Rapid and reliable tailoring of the dose of controlled release tablets to suit an individual patient is a major challenge for personalized medicine. The aim of this work was to investigate the feasibility of using a fused deposition modelling (FDM) based 3D p... |
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Investigations on the transfer of porphyrin from o/w emulsion droplets to liposomes with two different methods.
Drug Dev. Ind. Pharm. 41(1) , 156-62, (2014) Due to their small particle size, colloidal fat emulsions are suitable for intravenous administration. In order to obtain information on their potential in vivo performance, it is important to find a simple and effective in vitro assay to evaluate the drug re... |