4-氨基苯甲酸甲酯结构式
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常用名 | 4-氨基苯甲酸甲酯 | 英文名 | Methyl 4-aminobenzoate |
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| CAS号 | 619-45-4 | 分子量 | 151.163 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 299.2±13.0 °C at 760 mmHg | |
| 分子式 | C8H9NO2 | 熔点 | 110-111 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 154.9±17.4 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Tumor-preferential sustained drug release enhances antitumor activity of block copolymer micelles.
J. Drug Target. 22(7) , 619-28, (2014) Nanoparticles are widely used as drug carriers for controlled, tumor-targeted delivery of various anticancer agents that have biopharmaceutical limitations such as water solubility and tissue permeability. Growing evidence suggests that nanoparticles not only... |
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Application of stripping voltammetry to trace lead analysis in intermediates and final products of syntheses of pharmaceuticals.
J. Pharm. Biomed. Anal. 14(7) , 765-71, (1996) Applications of differential pulse anodic stripping voltammetry using a new pen-type renewed hanging mercury electrode have been investigated for trace analysis of lead in pharmaceutical substances and intermediates of their syntheses, such as procaine hydroc... |
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In Silico Estimation of Skin Concentration Following the Dermal Exposure to Chemicals.
Pharm. Res. 32 , 3965-74, (2015) To develop an in silico method based on Fick's law of diffusion to estimate the skin concentration following dermal exposure to chemicals with a wide range of lipophilicity.Permeation experiments of various chemicals were performed through rat and porcine ski... |
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Total synthesis of the alkaloids martinelline and martinellic acid via a hetero Diels-Alder multicomponent coupling reaction.
Org. Lett. 4(17) , 2913-6, (2002) [reaction: see text] A concise synthesis of the guanidine alkaloids, (+/-)-martinelline and (+/-)-martinellic acid, using a protic acid catalyzed 2:1 hetero Diels-Alder coupling reaction between N-Cbz 2-pyrroline and methyl 4-aminobenzoate, is described. Prot... |
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Efficient preparation of nitrosoarenes for the synthesis of azobenzenes.
J. Org. Chem. 70(6) , 2350-2, (2005) [reaction: see text] Reaction conditions are described for the oxidation of anilines furnishing nitrosoarenes and the synthesis of unsymmetrically substituted azobenzenes. In a comparative study, the catalytic oxidation of methyl 4-aminobenzoate by hydrogen p... |
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Topical drug delivery from thin applications: theoretical predictions and experimental results.
Pharm. Res. 7(10) , 1048-54, (1990) Stainless-steel templates of various thicknesses (75, 200, 800, and 1600 microns) were used to apply propylene glycol/water gels containing methyl or propyl p-aminobenzoates to silicone rubber membranes, and drug delivery was studied with the use of the Brona... |
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Formulation factors affecting release of drug from topical vehicles. II. Effect of solubility on in vitro delivery of a series of n-alkyl p-aminobenzoates.
J. Pharm. Sci. 84(6) , 673-6, (1995) The major influence on the rate of drug transfer out of its vehicle and into the skin is the thermodynamic activity of the drug within its formulation. This study addresses certain thermodynamic dependencies of topical delivery in a model system. Prototypical... |
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Cytotoxic metabolites from the wood-decayed fungus Xylaria sp. BCC 9653.
Chem. Pharm. Bull. 55(11) , 1647-8, (2007) Chemical investigation of the wood-decayed fungus Xylaria sp. BCC 9653 has led to the isolation of a new methyl aminobenzoate (1) together with eleven known compounds. The structures were established by analysis of spectroscopic data. Cytochalasin D (2), one ... |
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Butamben derivatives enhance BMP-2-stimulated commitment of C2C12 cells into osteoblasts with induction of voltage-gated potassium channel expression.
Bioorg. Med. Chem. Lett. 21 , 7363-6, (2011) As the primary step for 'drug repositioning', we evaluated the effect of 2000 drugs and drug candidates on the commitment of bi-potential mesenchymal precursor C2C12 cells into osteoblasts in the presence of bone morphogenetic protein (BMP)-2 and found that b... |