橄榄苦苷
橄榄苦苷结构式
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常用名 | 橄榄苦苷 | 英文名 | Oleuropein |
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| CAS号 | 32619-42-4 | 分子量 | 540.514 | |
| 密度 | 1.5±0.1 g/cm3 | 沸点 | 772.9±60.0 °C at 760 mmHg | |
| 分子式 | C25H32O13 | 熔点 | 89-90ºC | |
| MSDS | 中文版 美版 | 闪点 | 257.0±26.4 °C |
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Rapid screening of oleuropein from olive leaves using matrix solid-phase dispersion and high-performance liquid chromatography.
J. AOAC Int. 97(4) , 1109-13, (2014) Matrix solid-phase dispersion (MSPD) methodology as a quick and easy extraction method has been developed to extract oleuropein from Olea europaea leaves. This method has been compared with conventional maceration and Soxhlet extraction (SOXE) methods. Variab... |
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A metabolite-profiling approach to assess the uptake and metabolism of phenolic compounds from olive leaves in SKBR3 cells by HPLC-ESI-QTOF-MS.
J. Pharm. Biomed. Anal. 72 , 121-6, (2013) Olive leaves, an easily available natural low-cost material, constitute a source of extracts with significant antitumor activity that inhibits cell proliferation in several breast-cancer-cell models. In this work, a metabolite-profiling approach has been used... |
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Antiproliferative effect of oleuropein in prostate cell lines.
Int. J. Oncol. 41(1) , 31-8, (2012) Currently, there is increasing interest in the in vivo protective effects of natural antioxidants found in dietary plants against oxidative damage caused by free radical species. Oxidative stress has been invoked as a causative agent in cancer and epidemiolog... |
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Application of nanoLC-ESI-TOF-MS for the metabolomic analysis of phenolic compounds from extra-virgin olive oil in treated colon-cancer cells.
J. Pharm. Biomed. Anal. 63 , 128-34, (2012) Crude phenolic extracts (PE) have been obtained from naturally bearing Spanish extra-virgin olive oil (EVOO) showing different polyphenol families such as secoiridoids, phenolic alcohols, lignans, and flavones. EVOO-derived complex phenols (especially from th... |
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Characterisation and phenolic profiles of two rare olive oils from southern Tunisia: Dhokar and Gemri-Dhokar cultivars.
J. Sci. Food Agric. 93(3) , 527-34, (2013) The aim of this work was to study the chemical characteristics of two Tunisian cultivars, namely Dhokar and Gemri-Dhokar, to analyse the fatty acids, sterols, triacylglycerols, triterpenic alcohols, and to determine the phenolic composition and oxidative stab... |
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Oleuropein, chief constituent of olive leaf extract, prevents the development of morphine antinociceptive tolerance through inhibition of morphine-induced L-type calcium channel overexpression.
Phytother Res. 26(11) , 1731-7, (2012) It has been shown that blockade of L-type calcium channels could abolish the development of opioid-induced antinociceptive tolerance. Here, the antitolerant effects of olive leaf extract (OLE) and its main component, oleuropein, which have a calcium channel b... |
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Oleuropein prevents ethanol-induced gastric ulcers via elevation of antioxidant enzyme activities in rats.
J. Physiol. Biochem. 68(4) , 583-92, (2012) Purified oleuropein from olive leaf extract has been shown to have antioxidant effects in our recent studies. Thus, the aim of this study was to assess the antioxidant abilities of oleuropein in comparison with ranitidine in ethanol-induced gastric damages vi... |
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Neuroprotective effect of oleuropein following spinal cord injury in rats.
Neurol. Res. 34(1) , 44-51, (2012) Oleuropein (OE) is a well-known antioxidant polyphenol from olive oil. The purpose of this study was to determine the potential neuroprotective effects of oleuropein in an experimental spinal cord injury model.Rats were randomly divided into four groups of 21... |
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Oleuropein reduces free fatty acid-induced lipogenesis via lowered extracellular signal-regulated kinase activation in hepatocytes.
Nutr. Res. 32(10) , 778-86, (2012) Oleuropein, a bitter glucoside found in green olive leaves, and its metabolite hydroxytyrosol display powerful antioxidant activity both in vivo and in vitro. In this study, we hypothesized that the antioxidant activity of oleuropein could attenuate hepatic s... |
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Oleuropein induces anti-metastatic effects in breast cancer.
Asian Pac. J. Cancer Prev. 13(9) , 4555-9, (2012) Breast cancer causes death due to distant metastases in which tumor cells produce matrix metalloproteinase (MMP) enzymes which facilitate invasion. Oleuropein, the main olive oil polyphenol, has anti-proliferative effects. This study aimed to investigate the ... |