8-chloro-1-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-amine
![8-chloro-1-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-amine结构式](https://image.chemsrc.com/caspic/373/91896-57-0.png)
8-chloro-1-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-amine结构式
|
常用名 | 8-chloro-1-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-amine | 英文名 | 8-chloro-1-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-amine |
|---|---|---|---|---|
| CAS号 | 91896-57-0 | 分子量 | 295.72600 | |
| 密度 | 1.54g/cm3 | 沸点 | N/A | |
| 分子式 | C15H10ClN5 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
|
Autoradiographic comparison of the potency of several structurally unrelated adenosine receptor antagonists at adenosine A1 and A(2A) receptors.
Eur. J. Pharmacol. 380(2-3) , 197-202, (1999) We have examined the potency of several adenosine receptor antagonists at adenosine A1 and A2A receptors using quantitative autoradiography and have compared the results with those of previous studies using the same radioligands in membrane preparations. The ... |
|
|
Propentofylline inhibits polymorphonuclear leukocyte recruitment in vivo by a mechanism involving adenosine A2A receptors.
Eur. J. Pharmacol. 313(3) , 237-42, (1996) Propentofylline is an atypical xanthine derivative that blocks adenosine uptake and has been shown to protect against ischemia-induced cerebral damage. We have studied the effect of propentofylline on recruitment of polymorphonuclear leukocytes during acute p... |
|
|
Adenosine receptor-mediated modulation of acetylcholine release from rat striatal synaptosomes.
Br. J. Pharmacol. 110(3) , 949-54, (1993) 1. The effects of A1 and A2a adenosine receptor agonists on the veratridine-evoked release of [3H]-acetylcholine ([3H]-ACh) from rat striatal synaptosomes was investigated by use of the A1-selective agonist, R-PIA and the 185 fold selective A2a agonist, CGS 2... |
|
|
Adenosine A2 receptor regulation of apomorphine-induced turning in rats with unilateral striatal dopamine denervation.
Psychopharmacology 111(3) , 383-8, (1993) The ipsilateral intrastriatal administration of the specific adenosine A2a receptor agonist, 2-[p-(2-carboxyethyl)phenethylamino]-5'-N-ethylcarboxamido adenosine (CGS 21680), produced a dose related decrease in apomorphine-induced rotation in the unilaterally... |
|
|
Adenosine-induced relaxation of cultured bovine retinal pericytes.
Invest. Ophthalmol. Vis. Sci. 38(13) , 2695-701, (1997) To investigate the effect of adenosine on the contractile tone of cultured bovine retinal pericytes.Changes in the contractile tone were quantified as the changes in the summed length of wrinkles induced by pericytes on the silicone surface on which the cells... |
|
|
Interaction between adenosine A1 and A2 receptor-mediated responses in the rat hippocampus in vitro.
Eur. J. Pharmacol. 362(1) , 17-25, (1998) Previous work has been carried out on the effects of adenosine on transmitter release and on the excitability of postsynaptic neurones, but little is known about the effects of adenosine on the coupling between the two. In this study, we examine the effects o... |
|
|
Effects of the adenosine A1-receptor antagonist on defecation, small intestinal propulsion and gastric emptying in rats.
Jpn. J. Pharmacol. 68(1) , 119-23, (1995) We examined the effects of 1,3-dipropyl-8-cyclopentylxanthine (DPCPX) and (R)-7,8-dihydro-8-ethyl-2-(3-noradamantyl)-4-propyl-1H-imidazo[2,1 -i]purin- 5(4H)-one (KF20274), selective adenosine A1-receptor antagonists, on the gastrointestinal propulsion in rats... |
|
|
The effects of selective A1 and A2a adenosine receptor antagonists on cerebral ischemic injury in the gerbil.
Brain Res. 705(1-2) , 79-84, (1995) Cerebral ischemia of 5 min duration was induced in unanesthetized Mongolian gerbils by bilateral occlusion of the carotid arteries. The extent of ischemic injury was assessed behaviorally by measuring the increases in locomotor activity following ischemia and... |
|
|
Purinoceptor-mediated modulation by endogenous and exogenous agonists of stimulation-evoked [3H]noradrenaline release on rat iris.
Naunyn Schmiedebergs Arch. Pharmacol. 345(4) , 417-23, (1992) To investigate whether endogenous purinoceptor agonists affect the sympathetic neurotransmission in the rat isolated iris, and to classify the purinoceptors modulating exocytotic [3H]-noradrenaline release, we have determined the effect of adenosine receptor ... |
|
|
Adenosine (A2) antagonist inhibits induction of long-term potentiation of evoked synaptic potentials but not of the population spike in hippocampal CA1 neurons.
Biochem. Biophys. Res. Commun. 181(3) , 1010-4, (1991) The effects of adenosine A2 receptor antagonist (CP-66713) on long-term potentiation were studied using guinea pig hippocampal slices in a perfusion system. Tetanic stimulation of Schaffer collateral input which was applied during perfusion of CP-66713 (10 mi... |