抗菌肽A
抗菌肽A结构式
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常用名 | 抗菌肽A | 英文名 | Cecropin A |
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| CAS号 | 80451-04-3 | 分子量 | 4003.78 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C184H313N53O46 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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Lysylated phospholipids stabilize models of bacterial lipid bilayers and protect against antimicrobial peptides.
Biochim. Biophys. Acta 1838(9) , 2198-204, (2014) Aminoacylated phosphatidylglycerols are common lipids in bacterial cytoplasmic membranes. Their presence in Staphylococcus aureus has been linked to increased resistance to a number of antibacterial agents, including antimicrobial peptides. Most commonly, the... |
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Rgn gene is required for gut cell homeostasis after ingestion of sodium dodecyl sulfate in Drosophila.
Gene 549(1) , 141-8, (2014) Resistance and resilience constitute the two complementary aspects of epithelial host defenses in Drosophila. Epithelial cell homeostasis is necessary for the recovery of damages caused by stress or infections. However, the genes responsible for gut epithelia... |
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In vitro activities of antibiotics and antimicrobial cationic peptides alone and in combination against methicillin-resistant Staphylococcus aureus biofilms.
Antimicrob. Agents Chemother. 56(12) , 6366-71, (2012) Methicillin-resistant Staphylococcus aureus (MRSA) strains are most often found as hospital- and community-acquired infections. The danger of MRSA infections results from not only the emergence of multidrug resistance but also the occurrence of bacteria that ... |
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Localized permeabilization of E. coli membranes by the antimicrobial peptide Cecropin A.
Biochemistry 52(38) , 6584-94, (2013) Fluorescence microscopy enables detailed observation of the effects of the antimicrobial peptide Cecropin A on the outer membrane (OM) and cytoplasmic membrane (CM) of single E. coli cells with subsecond time resolution. Fluorescence from periplasmic GFP deca... |
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Spectroscopic and computational study of melittin, cecropin A, and the hybrid peptide CM15.
J. Phys. Chem. B 116(35) , 10600-8, (2012) Antimicrobial peptides (AMPs), such as cecropin A from silk moth, are key components of the innate immune system. They are effective defensive weapons against invading pathogens, yet they do not target host eukaryotic cells. In contrast, peptide toxins, such ... |
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Differential regulation of mRNA stability controls the transient expression of genes encoding Drosophila antimicrobial peptide with distinct immune response characteristics.
Nucleic Acids Res. 37 , 6550-61, (2009) The tight regulation of transiently expressed antimicrobial peptides (AMPs) with a distinct antimicrobial spectrum and different expression kinetics contributes greatly to the properly regulated immune response for resistance to pathogens and for the maintena... |
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Gene therapy with biosynthetic nanoscale peptide Cecropin A driven by the survivin promoter for hepatocarcinoma cells.
J. Biomed. Nanotechnol. 10(7) , 1391-9, (2014) The biosynthetic nanoscale peptide Cecropin A is postulated to disrupt microbial phospholipid membranes by forming stable or transient pores. We demonstrated previously that green fluorescent protein (GFP), driven by the survivin promoter, was expressed highl... |
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Trypanosoma cruzi: synergistic cytotoxicity of multiple amphipathic anti-microbial peptides to T. cruzi and potential bacterial hosts.
Exp. Parasitol. 125(4) , 342-7, (2010) The parasite Trypanasoma cruzi is responsible for Chagas disease and its triatomine vector, Rhodnius prolixus, has a symbiotic relationship with the soil bacterium, Rhodococcus rhodnii. R. rhodnii that was previously genetically engineered to produce the anti... |
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Modeling horizontal gene transfer (HGT) in the gut of the Chagas disease vector Rhodnius prolixus.
Parasit. Vectors 4 , 77, (2011) Paratransgenesis is an approach to reducing arthropod vector competence using genetically modified symbionts. When applied to control of Chagas disease, the symbiont bacterium Rhodococcus rhodnii, resident in the gut lumen of the triatomine vector Rhodnius pr... |
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Polymersome surface decoration by an EGFP fusion protein employing Cecropin A as peptide "anchor".
J. Biotechnol. 157(1) , 31-7, (2012) Polymer based nanocompartments have potential applications in synthetic biology, medicine (drug release) and industrial biotechnology (chiral nanoreactors, multistep syntheses, selective product recovery). A step towards the aforementioned goals is the polyme... |