奥芬达唑

奥芬达唑结构式
奥芬达唑结构式
品牌特惠专场
常用名 奥芬达唑 英文名 Oxfendazole
CAS号 53716-50-0 分子量 315.347
密度 1.5±0.1 g/cm3 沸点 N/A
分子式 C15H13N3O3S 熔点 253ºC
MSDS 中文版 美版 闪点 N/A
符号 GHS07
GHS07
信号词 Warning

Development and validation of an ultra high performance liquid chromatography tandem mass spectrometry method for simultaneous determination of sulfonamides, quinolones and benzimidazoles in bovine milk.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 962 , 20-9, (2014)

A simple, sensitive and reliable analytical method was developed for the simultaneous determination of 38 veterinary drugs (18 sulfonamides, 11 quinolones and 9 benzimidazoles) and 8 metabolites of benzimidazoles in bovine milk by ultra high performance liqui...

The effect of feed intake on the rate of flow of digesta and the disposition and activity of oxfendazole in sheep.

Int. J. Parasitol. 23(4) , 477-84, (1993)

Within 3 h of intra-ruminal (IR) administration oxfendazole (OFZ) was extensively associated with digesta particulate material. This association appeared to be a passive adsorption/desorption since sheep given dose equivalent OFZ which was contained solely in...

Preparation, characterization and application of a new stir bar sorptive extraction based on poly(vinylphthalimide-co-N,N'-methylenebisacrylamide) monolith.

J. Sep. Sci. 34(23) , 3418-25, (2011)

In this study, a new stir bar sorptive extraction (SBSE) coating based on poly(vinylphthalimide-co-N,N'-methylenebisacrylamide) monolith (SBSE-VPMB) was prepared. The influences of the contents of monomer in polymerization mixture and the percentage of poroge...

Gene expression analyses of the liver in rats treated with oxfendazole.

Arch. Toxicol. 81(9) , 647-54, (2007)

The effect of oxfendazole (OX), a benzimidazole anthelmintic, on hepatic gene expression was investigated in the liver of rats as a preliminary study to elucidate the possible mechanism of its non-genotoxic hepatocarcinogenesis. The liver from a male F344/N r...

Evaluation of nitazoxanide and oxfendazole efficacy against cystic echinococcosis in naturally infected sheep.

Am. J. Trop. Med. Hyg. 80(3) , 367-72, (2009)

Cystic echinococosis (CE) is a public health problem caused by Echinococcus granulosus. We aimed to determine the efficacy of nitazoxanide (NTZ) and oxfendazole (OXF) against CE in naturally infected sheep. A total of 151 ewes were assigned to the following g...

Evaluation of oxfendazole, praziquantel and albendazole against cystic echinococcosis: a randomized clinical trial in naturally infected sheep.

PLoS Negl. Trop. Dis. 4(2) , e616, (2010)

Cystic Echinococosis (CE) is a zoonotic disease caused by larval stage Echinococcus granulosus. We determined the effects of high dose of Oxfendazole (OXF), combination Oxfendazole/Praziquantel (PZQ), and combination Albendazole (ABZ)/Praziquantel against CE ...

Exploring flubendazole formulations for use in sheep. Pharmacokinetic evaluation of a cyclodextrin-based solution.

BMC Vet. Res. 8 , 71, (2012)

Flubendazole (FLBZ) is a poor water solubility broad-spectrum BZD methylcarbamate anthelmintic compound. Cyclodextrins (CDs) are usually used to increase aqueous solubility of poor hydrosoluble compounds. The comparative in vitro aqueous solubility of FLBZ an...

Efficacy of a single oral dose of oxfendazole against Fasciola hepatica in naturally infected sheep.

Am. J. Trop. Med. Hyg. 86(3) , 486-8, (2012)

The efficacy of a single oral dose of 30 mg/kg of oxfendazole against Fasciola hepatica was evaluated in a controlled study in naturally infected sheep. Sheep were diagnosed by stool microscopy after sedimentation, and positive animals were randomized to oxfe...

Immunohistochemical analyses at the late stage of tumor promotion by oxfendazole in a rat hepatocarcinogenesis model.

Arch. Toxicol. 85(2) , 155-62, (2011)

The present study was performed to characterize immunohistochemically the expression levels of molecules related to not only xenobiotic and antioxidant functions but also cell proliferation and apoptosis in neoplastic lesions induced by the benzimidazole anth...

Fecal egg count reductions and performance effect of Dectomax, Cydectin, and Cydectin plus Synanthic as used in feedlot steers.

Vet. Ther. 8(4) , 311-7, (2007)

A study was conducted to assess the effectiveness (fecal egg count reductions) and benefit (improvement in feed efficiency, average daily gain, health, and so forth) of a macrocyclic lactone (moxidectin [Cydectin Injectable] or doramectin [Dectomax 1% Injecta...