氟尼缩松

氟尼缩松结构式
氟尼缩松结构式
品牌特惠专场
常用名 氟尼缩松 英文名 Flunisolide
CAS号 3385-03-3 分子量 434.49800
密度 1.33g/cm3 沸点 581.8ºC at 760mmHg
分子式 C24H31FO6 熔点 237-240°C (dec.)
MSDS 中文版 美版 闪点 305.7ºC
符号 GHS06
GHS06
信号词 Danger

Detection and characterization of triamcinolone acetonide metabolites in human urine by liquid chromatography/tandem mass spectrometry after intramuscular administration.

Rapid Commun. Mass Spectrom. 28(16) , 1829-39, (2015)

Glucocorticosteroids are prohibited in sports when used by systemic administrations (e.g. intramuscular, IM), whereas they are allowed using other ways of administration. Strategies to discriminate between administrations routes have to be developed by doping...

Intranasal flunisolide treatment in patients with non-allergic rhinitis.

Int. J. Immunopathol. Pharmacol. 24(2) , 401-9, (2011)

Non-allergic rhinitis (NAR) is a heterogeneous disease, characterized by nasal hyperreactivity and inflammation. Its treatment is still debated, intranasal corticosteroids may be an option. The present study is aimed at evaluating the effect of the use of int...

Evaluation of efficacy and safety of flunisolide hydrofluoroalkane for the treatment of asthma.

Clin. Ther. 25(3) , 776-98, (2003)

Inhaled corticosteroids are currently recommended as first-line therapy for the long-term control and management of persistent asthma. Flunisolide hydrofluoroalkane (HFA) is a new formulation of the corticosteroid flunisolide that is delivered by a metered-do...

High-dose inhaled flunisolide versus budesonide in the treatment of acute asthma exacerbations in preschool-age children.

Int. J. Immunopathol. Pharmacol. 22(2) , 363-70, (2009)

The role of inhaled corticosteroids in asthma exacerbation is debated. We compared high doses of nebulized budesonide versus high doses of nebulized flunisolide, in association with a short-acting beta-2-agonist, in the treatment of moderate asthma exacerbati...

Late (≥ 7 days) inhalation corticosteroids to reduce bronchopulmonary dysplasia in preterm infants.

Cochrane Database Syst. Rev. 4 , CD002311, (2012)

Bronchopulmonary dysplasia (BPD), defined as oxygen dependence at 36 weeks postmenstrual age (PMA), remains an important complication of prematurity. Pulmonary inflammation plays a central role in the pathogenesis of BPD. Attenuating pulmonary inflammation wi...

Nebulized corticosteroids in asthma and COPD. An Italian appraisal.

Respir. Care 57(7) , 1161-74, (2012)

Inhaled corticosteroids (ICSs) are the mainstay of anti-inflammatory treatment in subjects with asthma and COPD. This review evaluates the role of nebulizers as an alternative to inhalers for delivering ICSs in asthma and COPD. I selected 16 randomized, place...

Recurrent acute rhinosinusitis: a single blind clinical study of N-acetylcysteine vs ambroxol associated to corticosteroid therapy.

Int. J. Immunopathol. Pharmacol. 25(1) , 207-17, (2012)

The aim of rhinosinusitis treatment is to restore sinusal eutrophism and to normalize ventilation and mucociliary transport. Frequently the improvement of sinusal physiological conditions is associated with a reduction of infections and pulmonary symptoms. Th...

A reappraisal of the clinical efficacy of nebulized flunisolide in pediatric asthma: the Italian experience.

Allergy Asthma Proc. 28(6) , 671-87, (2007)

Flunisolide (FLU) is a synthetic corticosteroid with potent topical anti-inflammatory activity. Its oral bioavailability is poor (6.7%). After gastrointestinal and lung absorption, the drug undergoes rapid and extensive first-pass metabolism by the liver to a...

Strength and endurance of the respiratory and handgrip muscles after the use of flunisolide in normal subjects.

Respir. Med. 101(7) , 1594-9, (2007)

To evaluate the effects of the inhaled flunisolide upon the strength and endurance of the respiratory and peripheral muscles of normal subjects.A randomized, double blind and placebo-controlled study.A university-affiliated teaching hospital.Thirteen normal v...

Nebulisation of corticosteroid suspensions and solutions with a beta(2) agonist.

J. Pharm. Pharmacol. 60(5) , 601-5, (2008)

The aim of this study was to determine the output of salbutamol nebulised in combination with either flunisolide or beclometasone dipropionate (BDP) from two different nebulisers under simulated breathing conditions. The BimboNeb and Nebula nebulisers were us...