灰叶草素, 羟基鱼藤素
灰叶草素, 羟基鱼藤素结构式
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常用名 | 灰叶草素, 羟基鱼藤素 | 英文名 | Tephrosin |
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| CAS号 | 76-80-2 | 分子量 | 410.417 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 623.4±55.0 °C at 760 mmHg | |
| 分子式 | C23H22O7 | 熔点 | 198° (218-220°) | |
| MSDS | 美版 | 闪点 | 219.3±25.0 °C | |
| 符号 |
GHS09 |
信号词 | Warning |
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[Rotenoids from Derris trifoliata].
Zhong Yao Cai 30(6) , 660-2, (2007) Five rotenoids named dehydrodeguelin, dehydrorotenone, 12a-hydroxy rotenone, tephrosin and 12alphabeta-hydroxyrot-2'-enonic acid were isolated from aerial parts of Derris trifoliata. All these compounds were isolated from this plant for the first time. |
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Preparative isolation and purification of three rotenoids and one isoflavone from the seeds of Millettia pachycarpa Benth by high-speed counter-current chromatography.
J. Chromatogr. A. 1178(1-2) , 101-7, (2008) Both analytical and preparative high-speed counter-current chromatography (HSCCC) were used to isolate and separate chemical bioactive constituents from the seeds of Millettia pachycarpa Benth, a famous traditional Chinese medicine. Three rotenoids and one is... |
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Effect of rotenoids from the seeds of Millettia dura on larvae of Aedes aegypti.
Pest Manag. Sci. 59(10) , 1159-61, (2003) A crude chloroform extract of seeds of Millettia dura Dunn (Leguminosae) showed high activity (LC50 = 3.5 microg ml(-1) at 24 h) against second-instar larvae of the mosquito, Aedes aegypti L (Diptera: Culicidae). The rotenoids, deguelin and tephrosin, isolate... |
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Cytotoxic compounds from Mundulea chapelieri from the Madagascar Rainforest.
J. Nat. Prod. 67(3) , 454-6, (2004) Bioassay-guided fractionation of methanolic extracts of Mundulea chapelieri resulted in the isolation of two new flavonoids, isomundulinol (1) and 3-deoxy-MS-II (2), in addition to the eight known flavonoids 8-(3,3-dimethylallyl)-5,7-dimethoxyflavanone, MS-II... |
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Phenolic constituents of Amorpha fruticosa that inhibit NF-kappaB activation and related gene expression.
J. Nat. Prod. 71(10) , 1696-700, (2008) NF-kappaB is known to play a crucial role in the regulation of genes controlling the immune system, apoptosis, tumor cell growth, and tissue differentiation. Bioassay-guided fractionation of the n-hexane-soluble fraction of a methanol extract of Amorpha fruti... |
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Concise modular asymmetric synthesis of deguelin, tephrosin and investigation into their mode of action.
Chemistry 16(32) , 9767-71, (2010)
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Rotenoids and flavonoids with anti-invasion of HT1080, anti-proliferation of U937, and differentiation-inducing activity in HL-60 from Erycibe expansa.
Bioorg. Med. Chem. 15 , 1539-46, (2007) Principal rotenoids (deguelin, tephrosin, rotenone, and 12a-hydroxyrotenone) (3-30microM) isolated from the stems of Erycibe expansa significantly inhibited invasion of human fibrosarcoma HT1080 cells through Matrigel-coated filters and release of proMMPs-2 a... |
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Pierreiones A-D, solid tumor selective pyranoisoflavones and other cytotoxic constituents from Antheroporum pierrei.
J. Nat. Prod. 74 , 852-6, (2011) Bioassay-guided fractionation of a solid tumor selective extract of the leaves and twigs of Antheroporum pierrei acquired from the U.S. National Cancer Institute extract repository afforded four new pyranoisoflavones, pierreiones A-D (1-4), together with rote... |
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Phthalides from Pittosporum illicioides var. illicioides with inhibitory activity on superoxide generation and elastase release by neutrophils.
J. Nat. Prod. 71 , 1692-5, (2008) Six new phthalides, (S)-3-ethyl-7-hydroxy-6-methoxyphthalide (1), (S)-3-ethyl-7-hydroxy-5,6-dimethoxyphthalide (2), (S)-3-ethyl-5,6,7-trimethoxyphthalide (3), (R)-3-ethyl-7-hydroxy-6-methoxyphthalide (4), (Z)-3-ethylidene-7-hydroxy-6-methoxyphthalide (5), and... |
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Two unusual rotenoid derivatives, 7a-O-methyl-12a-hydroxydeguelol and spiro-13-homo-13-oxaelliptone, from the seeds of Derris trifoliata.
Phytochemistry 67(10) , 988-91, (2006) The crude methanol extract of the seeds of Derris trifoliata showed potent and dose dependent larvicidal activity against the 2nd instar larvae of Aedes aegypti. From this extract two unusual rotenoid derivatives, a rotenoloid (named 7a-O-methyl-12a-hydroxyde... |