依托红霉素

依托红霉素结构式
依托红霉素结构式
品牌特惠专场
常用名 依托红霉素 英文名 Erythromycin Estolate
CAS号 3521-62-8 分子量 1000.324
密度 1.0053 (rough estimate) 沸点 827.7ºC at 760 mmHg
分子式 C52H97NO18S 熔点 135-140ºC dec.
MSDS 中文版 美版 闪点 454.4ºC
符号 GHS07 GHS08
GHS07, GHS08
信号词 Danger

Protective effect of Livex, a herbal formulation against erythromycin estolate induced hepatotoxicity in rats.

J. Ethnopharmacol. 57(3) , 161-7, (1997)

Livex, a compound herbal formulation, was investigated for its possible hepatoprotective effect in Wistar rats against erythromycin estolate induced toxicity. Oral administration of Livex significantly prevented the occurrence of erythromycin estolate induced...

Preparation and characterization of biodegradable poly(l-lactide)/poly(ethylene glycol) microcapsules containing erythromycin by emulsion solvent evaporation technique.

J. Colloid. Interface Sci. 271(2) , 336-41, (2004)

In this work, the producing of a biodegradable poly(l-lactide) (PLA)/poly(ethylene glycol) (PEG) microcapsule by emulsion solvent evaporation method was investigated. The effect of PEG segments added to the PLA microcapsules on the degradation, size distribut...

Pharmacokinetics of erythromycin estolate and erythromycin phosphate after intragastric administration to healthy foals.

Am. J. Vet. Res. 61(8) , 914-9, (2000)

To determine pharmacokinetics and plasma concentrations of erythromycin and related compounds after intragastric administration of erythromycin phosphate and erythromycin estolate to healthy foals.11 healthy 2- to 6-month-old foals.Food was withheld from foal...

Five days of erythromycin estolate versus ten days of penicillin V in the treatment of group A streptococcal tonsillopharyngitis in children. Pharyngitis Study Group.

Eur. J. Clin. Microbiol. Infect. Dis. 15(9) , 712-7, (1996)

In a randomized, prospective, multicenter trial, 227 children ranging in age from 3 to 17 years who had tonsillopharyngitis and a throat culture positive for group A beta-hemolytic streptococci (GABHS) were treated with erythromycin estolate (40 mg/kg/d in tw...

Pharmacokinetics of erythromycin after the administration of intravenous and various oral dosage forms to dogs.

J. Vet. Pharmacol. Ther. 31(6) , 496-500, (2008)

The purpose of this study was to describe and compare the pharmacokinetic properties of different formulations of erythromycin in dogs. Erythromycin was administered as lactobionate (10 mg/kg, IV), estolate tablets (25 mg/kg p.o.) and ethylsuccinate tablets o...

Multicenter, randomized, double-blind comparison of erythromycin estolate versus amoxicillin for the treatment of acute otitis media in children. AOM Study Group.

Eur. J. Clin. Microbiol. Infect. Dis. 17(7) , 470-8, (1998)

Erythromycin is frequently prescribed in Germany for acute otitis media, but well-designed clinical trials under present epidemiological conditions are lacking. Therefore, a double-blind, randomized, multicenter trial was performed to compare the clinical eff...

Use of erythromycin for the treatment of severe chronic constipation in children.

Braz. J. Med. Biol. Res. 36(10) , 1391-6, (2003)

The efficacy of erythromycin was assessed in the treatment of 14 children aged 4 to 13 years with refractory chronic constipation, and presenting megarectum and fecal impaction. A double-blind, placebo- controlled, crossover study was conducted at the Pediatr...

Protective effect of Sesbania grandiflora against erythromycin estolate-induced hepatotoxicity.

Therapie. 58(5) , 439-43, (2003)

Sesbania grandiflora, commonly known as 'sesbania', is widely used in Indian folk medicine for the treatment of liver disorders. Oral administration of an ethanolic extract of S. grandiflora leaves (200 mg/kg/day) for 15 days produced significant hepatoprotec...

[Comparison of the bioavailabilities of erythromycin estolate and erythromycin ethylsuccinate dry suspension preparations in steady state].

Pharmazie 50(1) , 56-60, (1995)

Relative bioavailability of erythromycin was determined after multiple-dose administration of erythromycin estolate in comparison to erythromycin ethylsuccinate both given as oral suspensions to twelve healthy volunteers. The daily erythromycin dose of erythr...

Antibiotics for whooping cough (pertussis).

Cochrane Database Syst. Rev. (1) , CD004404, (2005)

Whooping cough is a highly contagious disease. Infants are the population at highest risk of severe disease and death. Erythromycin for 14 days is recommended for treatment and contact prophylaxis but this regime is considered inconvenient and prolonged. The ...