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2-溴丙烷

一般危化品
2-溴丙烷结构式
2-溴丙烷结构式
常用名 2-溴丙烷 英文名 2-Bromopropane
CAS号 75-26-3 分子量 122.992
密度 1.3±0.1 g/cm3 沸点 60.6±8.0 °C at 760 mmHg
分子式 C3H7Br 熔点 -89 °C
MSDS 中文版 美版 闪点 19.4±0.0 °C
符号 GHS02 GHS08
GHS02, GHS08
信号词 Danger

Halogenated derivatives QSAR model using spectral moments to predict haloacetic acids (HAA) mutagenicity.

Bioorg. Med. Chem. 16 , 5720-32, (2008)

The risk of the presence of haloacetic acids in drinking water as chlorination by-products and the shortage of experimental mutagenicity data for most of them requires a research work. This paper describes a QSAR model to predict direct mutagenicity for these...

Reproductive toxicology: current and future directions.

Biochem. Pharmacol. 62(12) , 1557-64, (2001)

During the 20th century, there has been an increased risk from environmental by-products that may be harmful to reproductive function in humans. Therefore, as the 21st century begins, it is appropriate to evaluate future directions within the field of reprodu...

Occupational reproductive function abnormalities and bladder cancer in Korea.

J. Korean Med. Sci. 25(Suppl) , S41-5, (2010)

The purpose of this study was to review occupational reproductive abnormalities and occupational bladder cancer in Korea and to discuss their toxicological implications. Reproductive dysfunction as a result of 2-bromopropane poisoning was first reported in Ko...

Effects of 1-bromopropane, 2-bromopropane, and 1,2-dichloropropane on the estrous cycle and ovulation in F344 rats.

Toxicol. Lett. 126(1) , 41-9, (2002)

The present study was performed to investigate comparatively the toxic effects of inhalation exposure of 1-bromopropane, 2-bromopropane, and 1,2-dichloropropane on reproductive physiology, particularly on the estrous cycle and spontaneous ovulation in female ...

Impairment of male rat reproductive function in F1 offspring from dams exposed to 2-bromopropane during gestation and lactation.

Reprod. Toxicol. 16(2) , 151-9, (2002)

The toxic effects of 2-bromopropane (2-BP) on the reproductive tracts of male F1 offspring from dams exposed to 2-BP during gestation and lactation were investigated. Ten pregnant (sperm-positive) Sprague-Dawley rats per group were exposed sc to 2-BP at 135, ...

Developmental effects of inhalation exposure to 2-bromopropane in rats.

Reprod. Toxicol. 18(3) , 431-7, (2004)

2-Bromopropane (2-BP), known as a reproductive and hematopoietic toxicant in humans, was assessed for developmental toxicity. Sprague-Dawley rats were exposed by inhalation to 2-BP at a concentration of 0 (control), 125, 250, 500, or 1000 ppm for 6 h per day,...

Development of a headspace gas chromatographic test for the quantification of 1- and 2-bromopropane in human urine.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 814(1) , 185-9, (2005)

A test procedure was developed for the detection and quantification of 1- and 2-bromopropane in human urine. 1-Bromopropane (1-BP) is a commonly used industrial solvent, and 2-bromopropane (2-BP) is often found as an impurity component in industrial grade 1-B...

Synthesis, characterization and in vtro identification of N7-guanine adduct of 2-bromopropane.

Arch. Pharm. Res. 25(1) , 39-44, (2002)

Recently, we have reported that 2-bromopropane might have an immunotoxic potential in rats when exposed for 28 days. In the present studies, the possibility of 2i-deoxyguanosine adduct formation by 2-bromopropane was investigated in vitro to elucidate molecul...

Influence of 2-bromopropane on reproductive system--short-term administration of 2-bromopropane inhibits ovulation in F344 rats.

Toxicol. Ind. Health 16(7-8) , 277-83, (2000)

The present study was performed to investigate the toxic effects of 2-bromopropane (2BP) on the female reproductive system. Female F344 rats were administered 2BP (500 or 1000 mg/kg, i.p.) at intervals of 2 or 3 days for 15-17 days. The body weights were meas...

Comparative investigation of several sperm analysis methods for evaluation of spermatotoxicity of industrial chemical: 2-bromopropane as an example.

Ind. Health 42(2) , 219-25, (2004)

Reproductive toxicity of 2-bromopropane (2BP), a substitute for ozone layer-depleting chloro-fluorocarbon, was found among the workers in an electronics factory in Korea in 1995. Furthermore the importance of testicular toxicity has been realized since the pr...