2-溴丙烷结构式
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常用名 | 2-溴丙烷 | 英文名 | 2-Bromopropane |
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CAS号 | 75-26-3 | 分子量 | 122.992 | |
密度 | 1.3±0.1 g/cm3 | 沸点 | 60.6±8.0 °C at 760 mmHg | |
分子式 | C3H7Br | 熔点 | -89 °C | |
MSDS | 中文版 美版 | 闪点 | 19.4±0.0 °C | |
符号 |
GHS02, GHS08 |
信号词 | Danger |
Halogenated derivatives QSAR model using spectral moments to predict haloacetic acids (HAA) mutagenicity.
Bioorg. Med. Chem. 16 , 5720-32, (2008) The risk of the presence of haloacetic acids in drinking water as chlorination by-products and the shortage of experimental mutagenicity data for most of them requires a research work. This paper describes a QSAR model to predict direct mutagenicity for these... |
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Reproductive toxicology: current and future directions.
Biochem. Pharmacol. 62(12) , 1557-64, (2001) During the 20th century, there has been an increased risk from environmental by-products that may be harmful to reproductive function in humans. Therefore, as the 21st century begins, it is appropriate to evaluate future directions within the field of reprodu... |
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Occupational reproductive function abnormalities and bladder cancer in Korea.
J. Korean Med. Sci. 25(Suppl) , S41-5, (2010) The purpose of this study was to review occupational reproductive abnormalities and occupational bladder cancer in Korea and to discuss their toxicological implications. Reproductive dysfunction as a result of 2-bromopropane poisoning was first reported in Ko... |
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Effects of 1-bromopropane, 2-bromopropane, and 1,2-dichloropropane on the estrous cycle and ovulation in F344 rats.
Toxicol. Lett. 126(1) , 41-9, (2002) The present study was performed to investigate comparatively the toxic effects of inhalation exposure of 1-bromopropane, 2-bromopropane, and 1,2-dichloropropane on reproductive physiology, particularly on the estrous cycle and spontaneous ovulation in female ... |
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Impairment of male rat reproductive function in F1 offspring from dams exposed to 2-bromopropane during gestation and lactation.
Reprod. Toxicol. 16(2) , 151-9, (2002) The toxic effects of 2-bromopropane (2-BP) on the reproductive tracts of male F1 offspring from dams exposed to 2-BP during gestation and lactation were investigated. Ten pregnant (sperm-positive) Sprague-Dawley rats per group were exposed sc to 2-BP at 135, ... |
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Developmental effects of inhalation exposure to 2-bromopropane in rats.
Reprod. Toxicol. 18(3) , 431-7, (2004) 2-Bromopropane (2-BP), known as a reproductive and hematopoietic toxicant in humans, was assessed for developmental toxicity. Sprague-Dawley rats were exposed by inhalation to 2-BP at a concentration of 0 (control), 125, 250, 500, or 1000 ppm for 6 h per day,... |
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Development of a headspace gas chromatographic test for the quantification of 1- and 2-bromopropane in human urine.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 814(1) , 185-9, (2005) A test procedure was developed for the detection and quantification of 1- and 2-bromopropane in human urine. 1-Bromopropane (1-BP) is a commonly used industrial solvent, and 2-bromopropane (2-BP) is often found as an impurity component in industrial grade 1-B... |
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Synthesis, characterization and in vtro identification of N7-guanine adduct of 2-bromopropane.
Arch. Pharm. Res. 25(1) , 39-44, (2002) Recently, we have reported that 2-bromopropane might have an immunotoxic potential in rats when exposed for 28 days. In the present studies, the possibility of 2i-deoxyguanosine adduct formation by 2-bromopropane was investigated in vitro to elucidate molecul... |
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Influence of 2-bromopropane on reproductive system--short-term administration of 2-bromopropane inhibits ovulation in F344 rats.
Toxicol. Ind. Health 16(7-8) , 277-83, (2000) The present study was performed to investigate the toxic effects of 2-bromopropane (2BP) on the female reproductive system. Female F344 rats were administered 2BP (500 or 1000 mg/kg, i.p.) at intervals of 2 or 3 days for 15-17 days. The body weights were meas... |
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Comparative investigation of several sperm analysis methods for evaluation of spermatotoxicity of industrial chemical: 2-bromopropane as an example.
Ind. Health 42(2) , 219-25, (2004) Reproductive toxicity of 2-bromopropane (2BP), a substitute for ozone layer-depleting chloro-fluorocarbon, was found among the workers in an electronics factory in Korea in 1995. Furthermore the importance of testicular toxicity has been realized since the pr... |