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AC-GLN-LYS-LEU-VAL-PHE-PHE-NH2

AC-GLN-LYS-LEU-VAL-PHE-PHE-NH2结构式
AC-GLN-LYS-LEU-VAL-PHE-PHE-NH2结构式
品牌特惠专场
常用名 AC-GLN-LYS-LEU-VAL-PHE-PHE-NH2 英文名 Acetyl-Amyloid β-Protein (15-20) amide trifluoroacetate salt
CAS号 189064-06-0 分子量 822.99000
密度 N/A 沸点 N/A
分子式 C42H62N8O9 熔点 N/A
MSDS 美版 闪点 N/A

Arrest of beta-amyloid fibril formation by a pentapeptide ligand.

J. Biol. Chem. 271 , 8545-8548, (1996)

Polymerization of amyloid beta-peptide (Abeta) into amyloid fibrils is a critical step in the pathogenesis of Alzheimer's disease. Here, we show that peptides incorporating a short Abeta fragment (KLVFF; Abeta16-20) can bind full-length Abeta and prevent its ...

Controlling amyloid beta-peptide fibril formation with protease-stable ligands.

J. Biol. Chem. 272 , 12601-12605, (1997)

We have previously shown that short peptides incorporating the sequence KLVFF can bind to the approximately 40amino acid residue Alzheimer amyloid beta-peptide (Abeta) and disrupt amyloid fibril formation (Tjernberg, L. O., Näslund, J., Lindqvist, F., Johanss...