玫红酸结构式
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常用名 | 玫红酸 | 英文名 | Aurin |
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| CAS号 | 603-45-2 | 分子量 | 290.31 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 543.0±50.0 °C at 760 mmHg | |
| 分子式 | C19H14O3 | 熔点 | ca. 308ºC (decomposes) | |
| MSDS | 美版 | 闪点 | 296.2±26.6 °C |
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Ligand polarizability contributes to tau fibril binding affinity.
Bioorg. Med. Chem. 19 , 5147-54, (2011) Whole brain imaging of tau-bearing neurofibrillary lesions has the potential to improve the premortem diagnosis and staging of Alzheimer's disease. Diverse compounds with high affinity for tau aggregates have been reported from high-throughput screens, but th... |
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Screening of natural and synthetic drugs against Trypanosoma cruzi. 1. Establishing a structure/activity relationship.
Microbios 78(315) , 83-90, (1994) The activity of 45 compounds against bloodstream forms of Trypanosoma cruzi was investigated. The aim was to consider new agents which might subsequently be assayed for chemoprophylaxis in donated blood. In a preliminary screening the drugs were assayed (50 t... |
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Crystal structure analysis of oxidized Pseudomonas aeruginosa azurin at pH 5.5 and pH 9.0. A pH-induced conformational transition involves a peptide bond flip.
J. Mol. Biol. 221(3) , 765-72, (1991) The X-ray crystal structure of recombinant wild-type azurin from Pseudomonas aeruginosa was determined by difference Fourier techniques using phases derived from the structure of the mutant His35Leu. Two data sets were collected from a single crystal of oxidi... |
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Biological evaluation, chelation, and molecular modeling studies of novel metal-chelating inhibitors of NF-kappaB-DNA binding: structure activity relationships.
J. Med. Chem. 49 , 3595-601, (2006) Previously, we have reported that aurintricarboxylic acid (ATA) is one of the most potent inhibitors of the DNA binding of transcription factor NF-kappaB. We now report the NF-kappaB-DNA binding inhibitory activity of ATA analogues. An electrophoretic mobilit... |
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Aurintricarboxylic acid and Evans Blue represent two different classes of anionic compounds which selectively inhibit the cytopathogenicity of human T-cell lymphotropic virus type III/lymphadenopathy-associated virus.
Biochem. Biophys. Res. Commun. 136(1) , 64-71, (1986) Aurintricarboxylic acid, an anionic triphenylmethane dye, and Evans Blue, an anionic compound structurally related to suramin, are, like suramin itself, inhibitors of human T-cell lymphotropic virus type III (HTLV-III)/-lymphadenopathy-associated virus (LAV) ... |
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[Not Available].
Ann. Dermatol. Syphiligr. (Paris.) 6(9) , 504, (1946)
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[Not Available].
Riv. Crit. Clin. Med. 45(6-9) , 484-93, (1945)
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[Not Available].
Galicia. Clin. 18(12) , 741-3, (1946)
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Heparin potentiation of collagen-induced platelet aggregation is related to the GPIIb/GPIIIa receptor and not to the GPIb receptor, as tested by whole blood aggregometry.
Thromb. Res. 66(2-3) , 111-20, (1992) To determine whether heparin potentiation of platelet aggregation is related to platelet GP IIb/IIIa and GP Ib receptors, four series of experiments were performed on blood from normal volunteers. In the first experiment pretreatment with the monoclonal antib... |
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Differential activation of heme oxygenase-1 by chalcones and rosolic acid in endothelial cells.
J. Pharmacol. Exp. Ther. 312(2) , 686-93, (2005) The induction of heme oxygenase-1 (HO-1) is widely recognized as an effective cellular strategy to counteract a variety of stressful events. We have shown that curcumin and caffeic acid phenethyl ester, two naturally occurring phytochemicals that possess anti... |