氯化铈,无水

J. Org. Chem. 73(3) , 1121-3, (2008)

The preparation of the selective VEGF-R2 kinase inhibitor 10 (JNJ-17029259) is described in which the key precursor, 4-(5-isoxazolyl)benzonitrile, undergoes clean transformation to the corresponding cumylamine derivative with CeCl(3)-MeLi in THF. This high-yi...

J. Microbiol. Methods 86(1) , 97-103, (2011)

We developed a novel method using indirect staining with cerium chloride for visualization of the catechin derivative epigallocatechin gallate (EGCg) on the surface of particles, i.e., polystyrene beads and bacterial cells, by electron microscopy. The stainin...

Fish Physiol. Biochem. 36(3) , 367-76, (2010)

The antioxidative role of cerium was investigated in the liver of silver crucian carp injected with lead. The fish were intraperitoneally injected with 10, 20, or 30 mg/kg wet weight PbCl(2). After a 14-day period of incubation, 35 animals were injected with ...

Microsc. Res. Tech. 72(1) , 49-60, (2009)

Using quantitative X-ray microanalysis in combination with CeCl3-based cytochemical staining of hydrogen peroxide (H2O2) we have developed a new solution for quantification of H2O2 at the subcellular level. Quantitative X-ray microanalysis of plastic-embedded...

Biol. Trace Elem. Res. 142(2) , 174-89, (2011)

The organ toxicity of lanthanides (Ln) on organisms had been recognized, but very little is known about the oxidative injury of brain caused by Ln. In order to study the mechanisms underlying the effects of Ln on the brain, ICR mice were injected with a singl...

Biol. Trace Elem. Res. 140(3) , 317-29, (2011)

It has been proven that higher dose of lanthanoid (Ln) can induce liver toxicities, but the mechanisms and the molecular pathogenesis are still unclear. In this study, LaCl₃, CeCl₃, and NdCl₃ at a higher dose of 20 mg/kg body weight was injected into the abdo...

J. Trace Elem. Med. Biol. 22(1) , 59-65, (2008)

We evaluated tissue changes associated with cerium chloride administration via gavage to adult mice, via milk to neonatal mice and transplacentally to fetal mice. Change in adults consisted of extensive pulmonary hemorrhage, pulmonary venous congestion, thick...

Biol. Trace Elem. Res. 150(1-3) , 214-20, (2012)

The organophosphorus pesticide poisoning of the silkworm Bombyx mori is one of the major events causing serious damage to sericulture. Added low-dose rare earths are demonstrated to increase resistance in animals. However, very little is known about whether o...

Microsc. Res. Tech. 76(2) , 121-5, (2013)

The bacterial endogenous hydrogen peroxide (H(2)O(2)) was detected cytochemically by its reaction with cerium chloride (CeCl(3)) to produce electron-dense deposits of cerium perhydroxides. The sequence of fixation and CeCl(3) staining of H(2)O(2) in the proce...

Biol. Trace Elem. Res. 143(1) , 437-45, (2011)

Cerium (Ce) was shown to cause various toxic effects both in rats and mice; however, the molecular mechanism by which Ce exert theirs toxicity is still understood. In this report, the impairment of liver DNA conformation and liver apoptosis of mice caused by ...