2,3,4,5,6-五氟溴苄
2,3,4,5,6-五氟溴苄结构式
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常用名 | 2,3,4,5,6-五氟溴苄 | 英文名 | Pentafluorobenzyl Bromide |
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| CAS号 | 1765-40-8 | 分子量 | 260.987 | |
| 密度 | 1.9±0.1 g/cm3 | 沸点 | 173.2±35.0 °C at 760 mmHg | |
| 分子式 | C7H2BrF5 | 熔点 | 19-20 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 82.8±0.0 °C | |
| 符号 |
GHS05 |
信号词 | Danger |
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Determination of bisphenol A, triclosan and their metabolites in human urine using isotope-dilution liquid chromatography-tandem mass spectrometry.
J. Chromatogr. A. 1348 , 97-104, (2014) Bisphenol A (BPA) and triclosan (TCS) are ubiquitous environmental phenols exhibiting endocrine disrupting activities that may be involved in various health disorders in humans. There is a need to measure separately free forms and conjugated metabolites becau... |
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[Ureido-¹⁵N]citrulline UPLC-MS/MS nitric oxide synthase (NOS) activity assay: development, validation, and applications to assess NOS uncoupling and human platelets NOS activity.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 965 , 173-82, (2014) In healthy human subjects, less than 0.2% of l-arginine is converted to l-citrulline and nitric oxide (NO) by NO synthases (NOS), a metabolic pathway present in all cell types. Assessment of NOS activity in vitro and in vivo by measuring l-citrulline or NO is... |
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LC-MS/MS and GC-MS/MS measurement of plasma and urine di-paracetamol and 3-nitro-paracetamol: Proof-of-concept studies on a novel human model of oxidative stress based on oral paracetamol administration
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 959 , 71-81, (2014) • Proof-of-concept studies in mice and humans by GC-MS/MS and LC-MS/MS. • Paracetamol is metabolized to di-paracetamol and 3-nitro-paracetamol. • di-Paracetamol and 3-nitro-paracetamol occur in plasma and urine. • Molar ratio of di-paracetamol or 3-nitro-para... |
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LC-MS/MS analysis of uncommon paracetamol metabolites derived through in vitro polymerization and nitration reactions in liquid nitrogen.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 966 , 171-8, (2014) Paracetamol (acetaminophen, APAP) is a commonly used analgesic drug. Known paracetamol metabolites include the glucuronide, sulfate and mercapturate. N-Acetyl-benzoquinonimine (NAPQI) is considered the toxic intermediate metabolite of paracetamol. In vitro an... |
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GC-MS/MS and LC-MS/MS studies on unlabelled and deuterium-labelled oleic acid (C18:1) reactions with peroxynitrite (O=N-O-O⁻) in buffer and hemolysate support the pM/nM-range of nitro-oleic acids in human plasma.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 964 , 172-9, (2014) Oleic acid (cis-9,10-octadecenoic acid) is the most abundant monounsaturated fatty acid in human blood. Peroxynitrite (ONOO(-)) is a short-lived species formed from the reaction of nitric oxide (NO) and superoxide (O2(-)). Peroxynitrite is a potent oxidizing ... |
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Measurement of urinary excretion of 5-hydroxymethyluracil in human by GC/NICI/MS: correlation with cigarette smoking, urinary TBARS and etheno DNA adduct.
Toxicol. Lett. 155(3) , 403-10, (2005) 5-Hydroxymethyluracil (5-HMU) is derived from radiation in addition to endogenous oxidative DNA damage and it is one of the most abundant DNA adducts. Human 5-HMU-DNA-glycosylase has been shown to repair this lesion. Whether urinary levels of 5-HMU is a valid... |
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Quantitative determination of wine polyfunctional mercaptans at nanogram per liter level by gas chromatography-negative ion mass spectrometric analysis of their pentafluorobenzyl derivatives.
J. Chromatogr. A. 1146(2) , 242-50, (2007) A fast method for the determination of aroma-powerful polyfunctional thiols at nanogram per liter level has been developed and applied to wine. A small volume of wine (6 mL) was extracted with 1.5 mL of benzene containing four internal standards. Pentafluorob... |
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Quantification of F2-isoprostanes as a reliable index of oxidative stress in vivo using gas chromatography-mass spectrometry (GC-MS) method.
Free Radic. Biol. Med. 47 , 1101-7, (2009) Free radical-induced lipid peroxidation has been implicated in a number of human diseases including atherosclerosis, cancer, and neurodegenerative diseases. F(2)-Isoprostanes (IsoPs) are isomers of prostaglandin PGF(2alpha) that are generated in vivo from the... |
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Determination of trace amounts of bisphenol A in urine by negative-ion chemical-ionization-gas chromatography/mass spectrometry.
Anal. Sci. 19(1) , 151-3, (2003) We improved an analytical method for determining trace amounts of bisphenol A (BPA) in urine. BPA was subjected to enzymolysis and then to solid phase extraction with a C18 cartridge. The extract was eluted with methanol, and the eluate was concentrated under... |
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Application of a pentafluorobenzyl bromide derivatization method in gas chromatography/mass spectrometry of trace levels of halogenated phenols in air, water and sediment samples.
Anal. Sci. 18(6) , 655-9, (2002) An analytical method using pentafluorobenzyl bromide (PFBB) derivatization and gas chromatography/mass spectrometry (GC/MS) has been applied to identify and quantify chloro-, bromo- and dichlorophenols in air, water and sediment samples. Phenols in air sample... |