毒毛旋花苷K

Prog. Clin. Biol. Res. 268B , 143-7, (1988)

Sud. Med. Ekspert. 32(2) , 35-6, (1989)

Private technique of extraction isolation and purification, chromatographic detection and photometric determination of zimarin in urine is suggested. Detection limit is 0.01 mg, determination limit is 0.1 mg of glycoside in 100 ml of urine. Method makes it po...

Minerva Anestesiol. 58(10) , 639-45, (1992)

Arzneimittelforschung 35(4) , 687-93, (1985)

Calcium antagonistic properties of nicardipine (YC-93), a 1,4-dihydropyridine derivative, were studied in isolated cerebral artery and cardiac tissues of rabbits and dogs. Calcium antagonism was assessed in electrically stimulated rabbit basilar artery. Nicar...

Gen. Pharmacol. 16(3) , 183-8, (1985)

Ouabain and K-strophanthoside promote an enhancement of Na+/K+-ATPase activity in a range of cardioglycoside concentrations from 100 nM to 100 pM, with a maximum (+30%) between 10 and 4 nM. Binding experiments with [3H]ouabain show upward-curved Scatchard plo...

Wien. Med. Wochenschr. 136(21-22) , 545-9, (1986)

The influence of 2 different cardiac pharmaceutics on the diastolic ventricular function (VF) in patients with ischaemic heart disease was examined. Diltiazem, a calcium antagonist, and k-strophanthine led to a reduction of time constant T of the isovolumic r...

J. Membr. Biol. 91(1) , 43-51, (1986)

Electrophysiological experiments were performed to analyze the Na+/K+-ATPase in full-grown prophase-arrested oocytes of Xenopus laevis. If the Na+/K+-ATPase is inhibited by dihydroouabain (DHO), the resting potential of the membrane of Na+-loaded oocytes may ...

Arzneimittelforschung 34(4) , 423-9, (1984)

In the anaesthetized cat, SCOA ( Miroton ), a product which contains extracts from Scilla , Convallaria , Oleander and Adonis , displays not only its well-known positive inotropic effect but has also constrictor effects on veins when applied in intravenous do...

J. Biol. Chem. 259(16) , 10533-8, (1984)

A radioiodinated, photoactive cardiac glycoside derivative, 4'-(3-iodo-4-azidobenzene sulfonyl)cymarin (IAC) was synthesized and used to label (Na+K+)-ATPase in crude membrane fractions. In the dark, IAC inhibited the activity of (Na+K+)-ATPase in electroplax...

Immunobiology 171(4-5) , 436-50, (1986)

Through the blockade of the Na-K-ATPase, ouabain inhibits several biochemical and biological events leading to the proliferation of activated lymphocytes. Since we already found that interleukin 1 production was not prevented by ouabain, we investigated by wh...