4-巯基吡啶

Cancer Invest. 17(6) , 396-401, (1999)

The complex formed by isopentane, as a model for the isoleucine residue present in the wild-type thymidylate synthase, with 4-mercaptopyridine as a fragment of the thymidylate synthase inhibitor Thymitaq (AG337) is investigated with ab initio quantum chemical...

Chem. Commun. (Camb.) 47(19) , 5482-4, (2011)

By investigating the influence of peptides on the assembling process of Au nanorods induced by 4-mercaptopyridine, two kinds of peptides were identified. The nature of peptides plays an important role in tailoring assembling, which makes potential peptide rec...

Arch. Biochem. Biophys. 234(2) , 487-96, (1984)

2,2'-Dithiodipyridine reacts rapidly with sheep liver cytoplasmic aldehyde dehydrogenase in the presence of NAD +, resulting in activation of the enzyme by 2 to 2.5-fold (when assayed in the usual way). This is followed by the slow loss of most of the enzyme ...

J. Biotechnol. 134(3-4) , 218-21, (2008)

The aim of the present work was to explore the use of heteroaromatic thiol compounds, namely derivatives of pyridine and pyrimidine, as redox reagents for the in vitro-refolding of a recombinantly expressed single-chain Fv fragment (scFvOx). The mixed disulfi...

Anal. Biochem. 146(2) , 429-30, (1985)

In 1982, methyl 2-pyridyl disulfide was reported as a new reagent for the titration of thiol groups in peptides and proteins and for their temporary blocking with the thiomethyl group [T. Kimura et al. (1982) Anal. Biochem. 122, 274-282]. We have synthesized ...

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 824(1-2) , 222-8, (2005)

Reaction between iodine and azide ion induced by mercaptopyridines and mercaptopyrimidines was utilized as a detection system in TLC and HPTLC. The developed plates were sprayed with a freshly prepared mixtures of sodium azide and starch solution adjusted to ...

Biochem. Biophys. Res. Commun. 257(3) , 851-4, (1999)

Recombinant human gastric lipase (rHGL) and three of its cysteine mutants (cysteine 227, 236, and 244 substitued for threonine or serine) were expressed in the baculovirus/insect cell system and purified to homogeneity by performing a two-step procedure. Subs...

Anal. Chem. 78(15) , 5622-5, (2006)

To date, a successful combination of surface-enhanced resonance Raman spectroscopy (SERRS) and electrochemistry to study heme proteins is inhibited by the problems raised by the prerequisite to use silver as electrode metal. This paper indicates an approach t...

Anal. Chem. 85(22) , 10702-9, (2013)

We report the fabrication of a homogeneous and highly dense gold nanorod (AuNR) assembly on electrospun polycaprolactone (PCL) fibers using electrostatic interaction as the driving force. Specifically, decoration of a poly(sodium 4-styrenesulfonate) (PSS) lay...

Langmuir 23(8) , 4340-5, (2007)

To combine voltammetric techniques with surface-enhanced resonance Raman scattering (SERRS), cytochrome c (cyt c) was immobilized on a roughened silver electrode chemically modified with a self-assembled monolayer (SAM) of 4-mercaptopyridine (PySH). All measu...