吡啶硫酮锌

Mar. Pollut. Bull. 62(5) , 1147-51, (2011)

Highlights ► Tributyltin was not the most toxic antifouling biocides for 12 marine species. ► Irgarol was more toxic than TBT on the growth of autotrophic species. ► Toxicity of copper pyrithione was comparable to that of TBT for most test species. ► Copper p...

Arch. Environ. Contam. Toxicol. 63(3) , 365-77, (2012)

Macroalgae depend on carbon-concentrating mechanisms (CCMs) to maintain a high photosynthetic activity under conditions of low carbon dioxide (CO(2)) availability. Because such conditions are prevalent in marine environments, CCMs are important for upholding ...

Comp. Biochem. Physiol. C. Toxicol. Pharmacol. 169 , 16-24, (2015)

New biocides such as the organometallic compound zinc pyrithione (ZnP) have been massively introduced by many countries in formulations of antifouling paints following the ban on tributyltin (TBT). The effects of sublethal concentrations (LC50=82.5 μM, i.e., ...

Antimicrob. Agents Chemother. 55(12) , 5753-60, (2011)

Zinc pyrithione (ZPT) is an antimicrobial material with widespread use in antidandruff shampoos and antifouling paints. Despite decades of commercial use, there is little understanding of its antimicrobial mechanism of action. We used a combination of genome-...

Br. J. Dermatol. 165 Suppl 2 , 18-23, (2011)

Pathogenesis of dandruff/seborrhoeic dermatitis (D/SD) involves Malassezia yeasts, leading to the most widely accepted treatment strategy of topical application of antifungal agents, usually from rinse-off shampoos. The scalp spatial distribution of Malassezi...

Br. J. Pharmacol. 165(7) , 2244-59, (2012)

DFNA2 is a frequent hereditary hearing disorder caused by loss-of-function mutations in the voltage-gated potassium channel KCNQ4 (Kv7.4). KCNQ4 mediates the predominant K(+) conductance, I(K,n) , of auditory outer hair cells (OHCs), and loss of KCNQ4 functio...

Int. J. Dermatol. 50(1) , 102-13, (2011)

Dandruff is a common scalp condition characterized by flakes, pruritus and sometimes mild erythema. These symptoms reflect underlying histopathologic and biochemical events that must be reversed if treatment is to be effective.This study aimed to better chara...

Chemosphere 87(11) , 1316-22, (2012)

Zinc pyrithione is used as an antifouling agent. However, the environmental impacts of zinc pyrithione have recently been of concern. Zinc induces diverse actions during oxidative stress; therefore, we examined the effect of zinc pyrithione on rat thymocytes ...

Toxicol. Lett. 204(2-3) , 164-73, (2011)

Highlights ► Zinc pyrithione (ZnPyr) is cytotoxic in human dermal fibroblasts. ► High ZnPyr induces p53- and p38-dependent response and mitochondrial apoptosis. ► Low ZnPyr induces weak stress response without affecting mitogenic signaling. ► Low ZnPyr stimul...

Int. J. Cosmet. Sci. 35(1) , 78-83, (2013)

Dandruff is a common complaint and is suffered by as much as half of the population at some time post puberty. The condition is characterized by the presence of flakes on the scalp and in the hair, and is often accompanied by itch. The most common treatment f...