2,6-二羟基蒽醌
2,6-二羟基蒽醌结构式
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常用名 | 2,6-二羟基蒽醌 | 英文名 | 2,6-DIHYDROXY-ANTHRAQUINONE |
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| CAS号 | 84-60-6 | 分子量 | 240.211 | |
| 密度 | 1.5±0.1 g/cm3 | 沸点 | 442.1±35.0 °C at 760 mmHg | |
| 分子式 | C14H8O4 | 熔点 | >320 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 235.3±22.4 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Phytoestrogens from the roots of Polygonum cuspidatum (Polygonaceae): structure-requirement of hydroxyanthraquinones for estrogenic activity.
Bioorg. Med. Chem. Lett. 11(14) , 1839-42, (2001) The methanolic extract from the roots of Polygonum (P.) cuspidatum was found to enhance cell proliferation at 30 or 100 microg/mL in MCF-7, an estrogen-sensitive cell line. By bioassay-guided separation from P. cuspidatum with the most potent activity, emodin... |
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Mutagenicity of anthraquinone and hydroxylated anthraquinones in the Ames/Salmonella microsome system.
Appl. Environ. Microbiol. 43(6) , 1354-9, (1982) The mutagenicity of anthracene, anthraquinone, and four structurally similar compounds of each was evaluated in the Ames/Salmonella microsome assay. Anthraquinone was shown to be mutagenic for strains TA1537, TA1538, and TA98 in the absence of rat liver homog... |
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A compact optical instrument with artificial neural network for pH determination.
Sensors (Basel.) 12 , 6746-63, (2012) The aim of this work was the determination of pH with a sensor array-based optical portable instrument. This sensor array consists of eleven membranes with selective colour changes at different pH intervals. The method for the pH calculation is based on the i... |
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High mobility emissive organic semiconductor.
Nat. Commun. 6 , 10032, (2015) The integration of high charge carrier mobility and high luminescence in an organic semiconductor is challenging. However, there is need of such materials for organic light-emitting transistors and organic electrically pumped lasers. Here we show a novel orga... |
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Exceptional activity of tannic acid among naturally occurring plant phenols in protecting against 7,12-dimethylbenz(a)anthracene-, benzo(a)pyrene-, 3-methylcholanthrene-, and N-methyl-N-nitrosourea-induced skin tumorigenesis in mice.
Cancer Res. 48(9) , 2361-5, (1988) Our recent studies have shown that naturally occurring dietary plant phenols such as tannic acid, quercetin, myricetin, and anthraflavic acid are capable of inhibiting polycyclic aromatic hydrocarbon (PAH) metabolism and subsequent PAH-DNA adduct formation in... |
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Inhibition of epidermal xenobiotic metabolism in SENCAR mice by naturally occurring plant phenols.
Cancer Res. 47(3) , 760-6, (1987) Naturally occurring plant phenols such as tannic acid, quercetin, myricetin, and anthraflavic acid have been shown to inhibit the mutagenicity of several bay-region diol-epoxides of polycyclic aromatic hydrocarbons including benzo(a)pyrene (BP). The present s... |
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Inhibition of polycyclic aromatic hydrocarbon-DNA adduct formation in epidermis and lungs of SENCAR mice by naturally occurring plant phenols.
Cancer Res. 47(3) , 767-73, (1987) Naturally occurring plant phenols such as tannic acid, quercetin, myricetin, and anthraflavic acid are known to inhibit the mutagenicity of several bay-region diol-epoxides of polycyclic aromatic hydrocarbons (PAHs). The binding of bay-region diol-epoxides of... |
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Anthraflavic acid inhibits the mutagenicity of the food mutagen IQ: mechanism of action.
Mutat. Res. 207(3-4) , 121-5, (1988) The ability of anthraflavic acid to inhibit the mutagenicity of IQ was investigated using the Ames test and employing hepatic activation systems from Aroclor 1254-pretreated rats. Incorporation of anthraflavic acid into the S9 mix caused a concentration-depen... |
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Induction of rat hepatic cytochrome P-450 I proteins by the antimutagen anthraflavic acid.
Food Chem. Toxicol. 26(11-12) , 909-15, (1988) Administration of the antimutagen anthraflavic acid to rats gave rise to significant increases in the hepatic microsomal O-deethylations of ethoxyresorufin and ethoxycoumarin, but not in the O-dealkylation of pentoxyresorufin nor in cytosolic glutathione S-tr... |
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Anthraflavic acid is a potent and specific inhibitor of cytochrome P-448 activity.
Biochim. Biophys. Acta 916(3) , 328-31, (1987) Consideration of the computer-optimised dimensions of anthraflavic acid indicates that it is essentially a planar molecule with a large area/depth ratio, that would preferentially interact with the polycyclic aromatic hydrocarbon-induced family of cytochrome ... |