四氨合硝酸铂

J. Gen. Physiol. 102(6) , 1031-56, (1993)

The effects of ruthenium red and the related compounds tetraamine palladium (4APd) and tetraamine platinum (4APt) were studied on the ryanodine activated Ca2+ release channel reconstituted in planar bilayers with the immunoaffinity purified ryanodine receptor...

J. Zhejiang Univ. Sci. B 6(3) , 222-6, (2005)

Let G be a weighted graph with adjacency matrix A=[a(ij)]. An Euclidean graph associated with a molecule is defined by a weighted graph with adjacency matrix D=[d(ij)], where for i not = j, d(ij) is the Euclidean distance between the nuclei i and j. In this m...

Int. J. Radiat. Oncol. Biol. Phys. 33(3) , 641-6, (1995)

Because radiation is known to damage cellular membranes, the purpose of this study was to determine whether irradiation of cultured cells might modify the cellular uptake of the chemotherapy agent carboplatin.Total intracellular platinum was measured using at...

Int. J. Radiat. Biol. 68(6) , 609-14, (1995)

Carboplatin (3.6 mM) and salmon sperm DNA (3 micrograms), either double-stranded (dsDNA) or denatured single-stranded) (ssDNA), were irradiated (100 Gy) under hypoxic or oxic conditions. The drug and DNA were mixed either before, during, or after irradiation,...

J. Comput. Aided Mol. Des. 24(3) , 225-35, (2010)

The potential energy surfaces of chiral tetraamine Pt(II) coordination complexes were computed at the B3LYP/LANL2DZ level of theory by a systematic variation of two dihedral angles: C12-C15-C34-C37 (theta) and C24-C17-C31-C48 (psi) employing a grid resolution...

J. Comb. Chem. 8(5) , 780-3, (2006)

The individual and combinatorial syntheses of individual as well as a mixture-based diversity of 195 112 platinum(II) coordination complexes of chiral tetraamines are described. The use of both solid-phase synthesis and solution phase follow-on approaches wer...

Occup. Med. (Lond.) 58(3) , 215-8, (2008)

Platinum salt sensitivity (PSS) is well recognized following occupational exposure to platinum salts, though specific platinum compounds have been suggested to be non-allergenic. We report on a cohort of autocatalyst workers exposed to tetraamine platinum dic...

Andrologie 32(4-5) , 303-10, (2000)

Hydrogen hexachloroplatinate, H2PtCl6, has been shown to induce the human sperm acrosome reaction in vitro. However, the molecular mechanism underlying this exocytic process has not been studied. Therefore, two structurally and chemically different platinum (...