异丙醇胺
异丙醇胺结构式
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常用名 | 异丙醇胺 | 英文名 | Amino-2-propanol |
|---|---|---|---|---|
| CAS号 | 78-96-6 | 分子量 | 75.110 | |
| 密度 | 0.9±0.1 g/cm3 | 沸点 | 159.9±13.0 °C at 760 mmHg | |
| 分子式 | C3H9NO | 熔点 | -2ºC | |
| MSDS | 中文版 美版 | 闪点 | 73.9±0.0 °C | |
| 符号 |
GHS05, GHS07 |
信号词 | Danger |
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Synergistic effect of pendant hydroxypropyl and pyrrolidine moieties randomly distributed along polymethacrylamide backbones on in vitro DNA-transfection.
Eur. J. Pharm. Biopharm. 90 , 38-43, (2015) In this work, the cationic monomer N-ethyl pyrrolidine methacrylamide (EPA) was copolymerized with the neutral monomer N-hydroxypropyl methacrylamide (HPMA) at different molar ratios obtaining linear random copolymers that were characterized and evaluated in ... |
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Role of Polymer Architecture on the Activity of Polymer-Protein Conjugates for the Treatment of Accelerated Bone Loss Disorders.
Biomacromolecules 16 , 2374-81, (2015) Polymers of similar molecular weights and chemical constitution but varying in their macromolecular architectures were conjugated to osteoprotegerin (OPG) to determine the effect of polymer topology on protein activity in vitro and in vivo. OPG is a protein t... |
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A colorimetric chiral sensor based on chiral crown ether for the recognition of the two enantiomers of primary amino alcohols and amines.
Chirality 23(4) , 349-53, (2011) A new colorimetric chiral sensor material consisting of three different functional sites such as chromophore (2,4-dinitrophenylazophenol dye), binding site (crown ether), and chiral barrier (3,3'-diphenyl-1,1'-binaphthyl group) was prepared and applied to the... |
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Polymer conjugates of doxorubicin bound through an amide and hydrazone bond: Impact of the carrier structure onto synergistic action in the treatment of solid tumours.
Eur. J. Pharm. Sci. 58 , 1-12, (2014) In this study, we describe the synthesis, physico-chemical characterisation and results of the in vitro and in vivo evaluation of the biological behaviour of N-(2-hydroxypropyl)methacrylamide-based (HPMA) copolymer conjugates bearing doxorubicin (DOX) partly ... |
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Novel IL-2-Poly(HPMA)Nanoconjugate Based Immunotherapy.
J. Biomed. Nanotechnol. 11 , 1662-73, (2015) Interleukin-2 (IL-2) possesses a strong stimulatory activity for activated T and NK cells and it is an attractive molecule for immunotherapy. Nevertheless, extremely short half-life and severe toxicities associated with high-dose IL-2 treatment are serious an... |
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Comparative application of microwave, ultrasonication, ultracentrifugation and conventional heating for preparation of sample as dinitrophenyl derivative for direct enantioseparation of certain amino alcohols and 1-amino-2-propanol from vitamin B12hydrolysate on α1-acid glycoprotein and β-cyclodextrin columns
J. Chromatogr. A. 1216(45) , 7941-5, (2009) Taking into account the structural similarities of amino alcohols with amino acids and in order to reduce time for derivatization unconventional approaches viz. microwave irradiation, ultrasonication and ultra centrifugation were applied for synthesis of dini... |
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The mechanism of action of ethanolamine ammonia-lyase, an adenosylcobalamin-dependent enzyme. Studies with isopropanolamine, a true substrate.
J. Biol. Chem. 255(15) , 7444-8, (1980) Ethanolamine ammonia-lyase catalyzes the adenosylcobalamin (AdoCbl)-dependent deamination of 1-amino-3-propanol (isopropanolamine) to acetone and NH3. During the course of the reaction a hydrogen is transferred from the carbinol carbon of the substrate to one... |
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Charge-transfer complexes of 4-nitrocatechol with some amino alcohols.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 75(3) , 970-7, (2010) Charge-transfer (CT) complexes formed from the reactions of 4-nitropyrocatechol (4-nCat) as an electron acceptor with four amino alcohols: 2-aminoethanol, 1-amino-2-propanol, 4-aminobutanol and N-(2-hydroxyethyl)-1,3-diaminopropane (NHEDAP) as electron donors... |
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Synthesis and biological evaluation of novel isopropanolamine derivatives as non-peptide human immunodeficiency virus protease inhibitors.
Chem. Pharm. Bull. 56(8) , 1147-52, (2008) Novel potential human immunodeficiency virus (HIV) protease inhibitors were designed by a combination of nelfinavir and amprenavir motifs. The designed compounds were prepared by a facile synthetic route and their stereochemistry was further confirmed by a st... |
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Molecular structure and hydrogen bonding of 2-aminoethanol, 1-amino-2-propanol, 3-amino-1-propanol, and binary mixtures with water studied by Fourier transform near-infrared spectroscopy and density functional theory calculations.
Appl. Spectrosc. 64(3) , 351-8, (2010) The effect of temperature and water content on the molecular structure and hydrogen bonding of 2-aminoethanol (2AE), 1-amino-2-propanol (2AP), and 3-amino-1-propanol (3AP) has been examined by Fourier transform near-infrared (FT-NIR) spectroscopy. The experim... |