3-甲基己二酸

Clin. Chem. 29(3) , 434-7, (1983)

The urine of two patients with Refsum's disease consistently contained 2,6-dimethyloctanedioic acid, a compound not normally found in human urine. In addition, their urines contained increased concentrations of 3-methylhexanedioic acid. These two compounds ma...

J. Lipid Res. 44(8) , 1481-8, (2003)

Adult Refsum disease (ARD) is associated with defective alpha-oxidation of phytanic acid (PA). omega-Oxidation of PA to 3-methyl-adipic acid (3-MAA) occurs although its clinical significance is unclear. In a 40 day study of a new ARD patient, where the plasma...

J. Am. Chem. Soc. 127(1) , 458-64, (2005)

The work described here concerns a challenge of general interest in supramolecular chemistry: the achievement of chiral helical organizations with controlled structures. This work provides a strategy to obtain supramolecular polymers in which a chiral helical...

Acta Neurol. Scand 68(4) , 231-40, (1983)

The urinary excretion of organic acids was examined in 509 cases with multiple sclerosis and in 50 age- and sex-matched controls. The concentrations of the acids were related to creatinine. No differences were found for compounds such as glycolic acid, 2-meth...

Lancet 1(8265) , 194-6, (1982)

J. Pharm. Sci. 89(3) , 346-54, (2000)

The variation in physical properties of crystals grown in the presence of additives or impurities have previously been attributed to lattice disorder developed during crystallization. Adipic acid crystallized in the presence of a variety of stereochemically r...

J. Inherit. Metab. Dis. 8 Suppl 2 , 147-8, (1985)

Lancet 1(8272) , 624, (1982)