氯仿
一般危化品
氯仿结构式
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常用名 | 氯仿 | 英文名 | Chloroform |
|---|---|---|---|---|
| CAS号 | 67-66-3 | 分子量 | 119.378 | |
| 密度 | 1.5±0.1 g/cm3 | 沸点 | 61.2±8.0 °C at 760 mmHg | |
| 分子式 | CHCl3 | 熔点 | -63 °C | |
| MSDS | 中文版 美版 | 闪点 | -22.0±14.0 °C | |
| 符号 |
GHS06, GHS08 |
信号词 | Danger |
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A survey of the interactome of Kaposi's sarcoma-associated herpesvirus ORF45 revealed its binding to viral ORF33 and cellular USP7, resulting in stabilization of ORF33 that is required for production of progeny viruses.
J. Virol. 89(9) , 4918-31, (2015) The ORF45 protein of Kaposi's sarcoma-associated herpesvirus (KSHV) is a gammaherpesvirus-specific immediate-early tegument protein. Our previous studies have revealed its crucial roles in both early and late stages of KSHV infection. In this study, we survey... |
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Aqueous-core PEG-coated PLA nanocapsules for an efficient entrapment of water soluble anticancer drugs and a smart therapeutic response.
Eur. J. Pharm. Biopharm. 89 , 30-9, (2015) Novel PEGylated PLA nanocapsules (PEG-AcPLA nanocapsules), loading high percentage of water soluble drugs have been formulated by using multiple emulsion technique without using conventional stabilizers. In particular, sodium deoxycholate hydrate has been use... |
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SSX2 is a novel DNA-binding protein that antagonizes polycomb group body formation and gene repression.
Nucleic Acids Res. 42(18) , 11433-46, (2014) Polycomb group (PcG) complexes regulate cellular identity through epigenetic programming of chromatin. Here, we show that SSX2, a germline-specific protein ectopically expressed in melanoma and other types of human cancers, is a chromatin-associated protein t... |
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The dynamics of giant unilamellar vesicle oxidation probed by morphological transitions.
Biochim. Biophys. Acta 1838(10) , 2615-24, (2014) We have studied the dynamics of Lissamine Rhodamine B dye sensitization-induced oxidation of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) giant unilamellar vesicles (GUVs), where the progression of the underlying chemical processes was followed via vesicle... |
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The dual FAAH/MAGL inhibitor JZL195 has enhanced effects on endocannabinoid transmission and motor behavior in rats as compared to those of the MAGL inhibitor JZL184.
Pharmacol. Biochem. Behav. 124 , 153-9, (2014) The biological actions of the endocannabinoids anandamide and 2-arachidonoyl glycerol (2-AG) are terminated by enzymatic hydrolysis of these lipids via fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL), respectively. While several selective... |
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Investigations on the transfer of porphyrin from o/w emulsion droplets to liposomes with two different methods.
Drug Dev. Ind. Pharm. 41(1) , 156-62, (2014) Due to their small particle size, colloidal fat emulsions are suitable for intravenous administration. In order to obtain information on their potential in vivo performance, it is important to find a simple and effective in vitro assay to evaluate the drug re... |
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Binding properties of antimicrobial agents to lipid membranes using surface plasmon resonance.
Biol. Pharm. Bull. 37(8) , 1383-9, (2014) In the present study, we examined the interaction of antimicrobial agents with four model lipid membranes that mimicked mammalian cell membranes and Gram-positive and -negative bacterial membranes and analyzed the binding kinetics using our surface plasmon re... |
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N6-methyladenosine marks primary microRNAs for processing.
Nature 519(7544) , 482-5, (2015) The first step in the biogenesis of microRNAs is the processing of primary microRNAs (pri-miRNAs) by the microprocessor complex, composed of the RNA-binding protein DGCR8 and the type III RNase DROSHA. This initial event requires recognition of the junction b... |
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Process development for scum to biodiesel conversion.
Bioresour. Technol. 185 , 185-93, (2015) A novel process was developed for converting scum, a waste material from wastewater treatment facilities, to biodiesel. Scum is an oily waste that was skimmed from the surface of primary and secondary settling tanks in wastewater treatment plants. Currently s... |
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Lateral opening of the bacterial translocon on ribosome binding and signal peptide insertion.
Nat. Commun. 5 , 5263, (2014) Proteins are co-translationally inserted into the bacterial plasma membrane via the SecYEG translocon by lateral release of hydrophobic transmembrane segments into the phospholipid bilayer. The trigger for lateral opening of the translocon is not known. Here ... |