2-溴苯乙酮结构式
|
常用名 | 2-溴苯乙酮 | 英文名 | 2-Bromoacetophenone |
---|---|---|---|---|
CAS号 | 70-11-1 | 分子量 | 199.045 | |
密度 | 1.5±0.1 g/cm3 | 沸点 | 253.4±0.0 °C at 760 mmHg | |
分子式 | C8H7BrO | 熔点 | 48-51 °C(lit.) | |
MSDS | 中文版 美版 | 闪点 | 78.4±7.2 °C | |
符号 |
GHS05 |
信号词 | Danger |
Structure-activity relationships of a novel pyranopyridine series of Gram-negative bacterial efflux pump inhibitors.
Bioorg. Med. Chem. 23(9) , 2024-34, (2015) Recently we described a novel pyranopyridine inhibitor (MBX2319) of RND-type efflux pumps of the Enterobacteriaceae. MBX2319 (3,3-dimethyl-5-cyano-8-morpholino-6-(phenethylthio)-3,4-dihydro-1H-pyrano[3,4-c]pyridine) is structurally distinct from other known G... |
|
Nucleophilic heterocyclic carbene as a novel catalyst for cyclopropanation of cyano acrylates.
Org. Biomol. Chem. 8(4) , 901-5, (2010) Nucleophilic heterocyclic carbenes (NHCs) have been used for the first time as catalysts in the cyclopropanation of ethyl cyanocinnamates with phenacyl bromide by Michael-initiated ring-closure (MIRC). |
|
Bromoacetophenone-based photonucleases: photoinduced cleavage of DNA by 4'-bromoacetophenone-pyrrolecarboxamide conjugates.
Org. Lett. 1(13) , 2117-20, (1999) [formula: see text] 4'-Bromoacetophenone derivatives which upon excitation can generate monophenyl radicals capable of hydrogen atom abstraction were investigated as photoinducible DNA cleaving agents. Pyrrolecarboxamide-conjugated 4'-bromoacetophenones were ... |
|
A convenient ultrasound-promoted synthesis of some new thiazole derivatives bearing a coumarin nucleus and their cytotoxic activity.
Molecules 17(8) , 9335-47, (2012) Successful implementation of ultrasound irradiation for the rapid synthesis of a novel series of 3-[1-(4-substituted-5-(aryldiazenyl)thiazol-2-yl)hydrazono)ethyl]-2H-chromen-2-ones 5a-h, via reactions of 2-(1-(2-oxo-2H-chromen-3-yl)ethylidene) thiosemicarbazi... |
|
Synthesis and biological activities of new substituted thiazoline-quinoline derivatives.
Acta. Pharm. 59(4) , 365-82, (2009) 5-Acyl-8-hydroxyquinoline-2-(3'-substituted-4'-aryl-2,3-dihydrothiazol-2'-ylidene)hydrazones, 5a-e to 10a-c, were prepared by the reaction of appropriate 5-acyl-8-hydroxyquinoline-4-substituted thiosemicarbazones 3a-e and phenacyl bromides 4a-e. Structures of... |
|
alpha-bromoacetophenone derivatives as neutral protein tyrosine phosphatase inhibitors: structure-Activity relationship.
Bioorg. Med. Chem. Lett. 12(21) , 3047-50, (2002) A series of alpha-haloacetophenone derivatives was tested for inhibition of protein tyrosine phosphatases SHP-1 and PTP1B. The results show that the bromides are much more potent than the corresponding chlorides, whereas the phenyl ring is remarkably tolerant... |
|
FT-IR and FT-Raman spectral investigation, computed IR intensity and Raman activity analysis and frequency estimation analysis on 4-chloro-2-bromoacetophenone using HF and DFT calculations.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 78(2) , 826-34, (2011) In this work, the experimental and theoretical spectra of 4-chloro-2-bromoacetophenone (4C2BAP) are studied. FT-IR and FT-Raman spectra of title molecule have been recorded in the region 4000-100 cm(-1). The structural and spectroscopic data of the molecule i... |
|
High-performance liquid chromatographic determination of cytosine-containing compounds by precolumn fluorescence derivatization with phenacyl bromide: application to antiviral nucleosides and nucleotides.
J. Chromatogr. B, Biomed. Appl. 679(1-2) , 119-27, (1996) A novel precolumn derivatization method for the HPLC determination of cytosine-containing compounds by HPLC is described. Highly fluorescent 2-phenyl-3,N4-ethenocytosine derivatives are produced by a reaction of non-fluorescent cytosine-containing compounds w... |
|
Measurement of plasma acetate kinetics using high-performance liquid chromatography.
Anal. Biochem. 198(1) , 149-53, (1991) Previous studies suggest that plasma acetate may be an important fuel in man, accounting for approximately 10% of energy expenditure. Available methods for the determination of plasma acetate kinetics are difficult and time consuming. We describe here a proce... |
|
Active-site residues of procarboxypeptidase Y are accessible to chemical modification.
Biochim. Biophys. Acta 1205(2) , 289-93, (1994) The accessibility of the active-site cleft of procarboxypeptidase Y from Saccharomyces cerevisiae has been studied by chemical modifications of two specific amino-acid residues. Previous studies have shown that these residues, Cys-341 and Met-398 in the matur... |