苄噻嗪

苄噻嗪结构式
苄噻嗪结构式
品牌特惠专场
常用名 苄噻嗪 英文名 Benzthiazide
CAS号 91-33-8 分子量 431.93700
密度 1.4176 (rough estimate) 沸点 680.6 °C at 760 mmHg
分子式 C15H14ClN3O4S3 熔点 231-232° (U.S. patent); mp 238-239° (P'an)
MSDS 中文版 美版 闪点 365.4 °C
符号 GHS08
GHS08
信号词 Danger

Interactions of diuretics with a neutral temperature-responsive polymer: study by capillary electroporesis and dynamic light scattering.

J. Capill. Electrophor. Microchip Technol. 6(5-6) , 163-8, (1999)

Interactions between diuretics and a recently synthesized temperature-responsive neutral copolymer, poly(N-isopropyl acrylamide) (PNIPA) grafted with poly(ethyleneoxide) (PEO) (PNIPA-g-PEO) were investigated by capillary electrophoresis and dynamic light scat...

Rational drug repositioning guided by an integrated pharmacological network of protein, disease and drug.

BMC Syst. Biol. 6 , 80, (2012)

The process of drug discovery and development is time-consuming and costly, and the probability of success is low. Therefore, there is rising interest in repositioning existing drugs for new medical indications. When successful, this process reduces the risk ...

Rapid screening for diuretic doping agents in urine by C60-assisted laser-desorption-ionization-time-of-flight mass spectrometry.

J. Anal. Toxicol. 23(5) , 337-42, (1999)

This study describes a matrix-assisted laser-desorption-ionization (MALDI) mass spectrometry for rapid screening of 12 diuretics in spiked urine. C60 is used as the matrix for MALDI. Diuretics are directly analyzed by C60-MALDI without previous derivatization...

Loop diuretic and anion modification of NEM-induced K transport in human red blood cells.

Am. J. Physiol. 258(4 Pt 1) , C622-9, (1990)

The thioalkylating agent N-ethylmaleimide (NEM) causes ouabain-insensitive K loss from human red blood cells. This K loss is inhibited when intracellular Cl is replaced by another permeant anion or when loop diuretics are placed in the incubation medium after...

Hypercalciuria in hyperprolactinemic rats: effects of benzthiazide.

Metab. Clin. Exp. 35(7) , 668-72, (1986)

There is evidence that prolactin (PRL) excess plays a role in the etiology of osteoporosis associated with human prolactinoma. Calcium balance in human hyperprolactinemia has not been thoroughly investigated. In the present study, rats with excess circulating...

HPLC determination of benzthiazide in biologic material.

Biopharm. Drug Dispos. 3(1) , 1-9, (1982)

An assay was developed for benzthiazide in plasma, urine and feces, using high performance liquid chromatography (HPLC). A reverse-phase column was employed, with quantitation af 280 nm, using polythiazide as an internal standard. In three of four human subje...

Thiazides XIII: Dissolution testing: a bioavailability predictor for benzthiazide tablets.

Biopharm. Drug Dispos. 3(3) , 283-5, (1982)