3,4-二氯苯乙酸
3,4-二氯苯乙酸结构式
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常用名 | 3,4-二氯苯乙酸 | 英文名 | 3,4-Dichlorophenylacetic acid |
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| CAS号 | 5807-30-7 | 分子量 | 205.038 | |
| 密度 | 1.5±0.1 g/cm3 | 沸点 | 328.0±27.0 °C at 760 mmHg | |
| 分子式 | C8H6Cl2O2 | 熔点 | 89-91 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 152.1±23.7 °C |
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Alterations in the stereochemistry of the kappa-selective opioid agonist U50,488 result in high-affinity sigma ligands.
J. Med. Chem. 32 , 1996, (1989) The synthesis and in vitro sigma receptor activity of the two diastereomers of U50,488 [(+/-)-2], namely, (1R,2S)-(+)- cis-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacet ami de [(+)-1] and (1S,2R)-(-)-cis-3,4-dichloro- N-methyl-N-[2-(1-pyrr... |
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4-[(Alkylamino)methyl]furo[3,2-c]pyridines: a new series of selective kappa-receptor agonists.
J. Med. Chem. 37 , 2138, (1994) The synthesis of 5-(arylacetyl)-4-[(alkylamino)methyl]furo[3,2-c] pyridines (16-23, 26, 27) and their activities as kappa-opioid receptor agonists are described. kappa-Agonist potency was particularly sensitive to the nature of the basic moiety. In particular... |
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