异硫氰酸三甲基硅酯结构式
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常用名 | 异硫氰酸三甲基硅酯 | 英文名 | trimethylsilyl isothiocyanate |
|---|---|---|---|---|
| CAS号 | 2290-65-5 | 分子量 | 131.27100 | |
| 密度 | 0.931 g/mL at 25 °C(lit.) | 沸点 | 143 °C(lit.) | |
| 分子式 | C4H9NSSi | 熔点 | −32.8 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 95 °F | |
| 符号 |
GHS02, GHS06, GHS08 |
信号词 | Danger |
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Multiple pathways in the synthesis of new annelated analogues of 6-benzyl-1-(ethoxymethyl)-5-isopropyluracil (emivirine).
Org. Biomol. Chem. 1(16) , 2908-18, (2003) Condensation of 3-(3,5-dimethylphenyl)-2-oxocyclopentanecarboxamide (11) with oxalyl chloride and condensation of ethyl 2-benzylamino-5-methyl-3-phenylcyclopent-1-enecarboxylate (17a) with trimethylsilyl isothiocyanate gave 7-(3,5-dimethylphenyl)-6,7-dihydro-... |
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Reactivity of fullerene epoxide: preparation of fullerene-fused thiirane, tetrahydrothiazolidin-2-one, and 1,3-dioxolane.
J. Org. Chem. 73(7) , 2518-26, (2008) The epoxide moiety in the fullerene-mixed peroxide C60(O)(OOtBu)4 1 reacts readily with aryl isocyanates ArNCS (Ar = Ph, Naph) to form both the thiirane derivative C60(S)(OOtBu)4 and fullerene-fused tetrahydrothiazolidin-2-one. The reaction of 1 with trimethy... |
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A method for preparation of amino acid thiohydantoins from free amino acids activated by acetyl chloride for development of protein C-terminal sequencing.
Anal. Biochem. 249(2) , 207-11, (1997) A novel and efficient method to prepare amino acid thiohydantoins, which are required as reference standards for development of C-terminal protein sequencing, is reported. Amino acid thiohydantoins were prepared using a straightforward method involving reacti... |
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Studies in C-terminal sequencing: new reagents for the synthesis of peptidylthiohydantoins.
J. Protein Chem. 12(2) , 195-205, (1993) In previous studies aimed at the sequencing of peptides and proteins from the carboxy terminus, we have derivatized the C-terminus to a thiohydantoin using acetic anhydride and trimethylsilylisothiocyanate (TMS-ITC) and subsequently hydrolyzed it to form a sh... |
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Microsequence analysis of peptides and proteins: trimethylsilylisothiocyanate as a reagent for COOH-terminal sequence analysis.
Anal. Biochem. 166(2) , 298-307, (1987) A reinvestigation of the isothiocyanate-based chemistry for cyclic degradations of peptides and proteins revealed that the reagent trimethylsilylisothiocyanate (TMS-ITC) gives superior results in terms of coupling efficiency and lack of complicating side reac... |
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Carboxy-terminal sequencing: formation and hydrolysis of C-terminal peptidylthiohydantoins.
Biochemistry 29(12) , 3145-56, (1990) Proteins and peptides can be sequenced from the carboxy terminus with isothiocyanate reagents to produce amino acid thiohydantoin derivatives. Previous studies in our laboratory indicated that the use of trimethylsilyl isothiocyanate (TMS-ITC) as a coupling r... |
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Noncatalyzed Addition of Trimethylsilyl Isothiocyanate to Aziridines and Cyclohexene Oxide. Prusinowska N and Gawronski J.
Synth. Commun. 39(15) , 2795-2803, (2009)
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