3,4-二氢-2(1H)-喹啉酮结构式
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常用名 | 3,4-二氢-2(1H)-喹啉酮 | 英文名 | 3,4-Dihydroquinolin-2(1H)-one |
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| CAS号 | 553-03-7 | 分子量 | 147.174 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 328.1±31.0 °C at 760 mmHg | |
| 分子式 | C9H9NO | 熔点 | 165-167ºC | |
| MSDS | 美版 | 闪点 | 189.4±9.8 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Synthesis and biological evaluation of a novel sigma-1 receptor antagonist based on 3,4-dihydro-2(1H)-quinolinone scaffold as a potential analgesic.
Eur. J. Med. Chem. 79 , 216-30, (2014) The synthesis and sigma-1 receptor (1R) antagonist activity of a new series of 3,4-dihydro-2(1H)-quinolinone derivatives are reported. The new compounds were evaluated in vitro in sigma-1 and sigma-2 receptor-binding assays in guinea pig brain membranes. The ... |
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Novel approach to 3,4-dihydro-2(1H)-quinolinone derivatives via cyclopropane ring expansion.
Org. Lett. 11(5) , 1043-5, (2009) N-(1'-Alkoxy)cyclopropyl-2-haloanilines are transformed to 3,4-dihydro-2((1)H)-quinolinones via palladium-catalyzed cyclopropane ring expansion. The reaction tolerates a variety of functional groups such as ester, nitrile, ether, and ketone groups. |
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Synthesis of 4-amino-3, 4-dihydro-2 (1H)-quinolinones via β-lactam intermediates on the solid-phase. Pei Y, et al.
Tetrahedron Lett. 38(19) , 3349-52, (1997)
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Selective removal of nitrogen from quinoline and petroleum by Pseudomonas ayucida IGTN9m. Kilbane JJ, et al.
Appl. Environ. Microbiol. 66(2) , 688-693, (2000)
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