马拉氧磷结构式
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常用名 | 马拉氧磷 | 英文名 | Malaoxon |
|---|---|---|---|---|
| CAS号 | 1634-78-2 | 分子量 | 314.292 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 376.0±52.0 °C at 760 mmHg | |
| 分子式 | C10H19O7PS | 熔点 | <20℃ | |
| MSDS | 中文版 美版 | 闪点 | 181.2±30.7 °C | |
| 符号 |
GHS06 |
信号词 | Danger |
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Acetylcholinesterase immobilized on magnetic beads for pesticides detection: application to olive oil analysis.
Sensors (Basel.) 12(6) , 7893-904, (2012) This work presents the development of bioassays and biosensors for the detection of insecticides widely used in the treatment of olive trees. The systems are based on the covalent immobilisation of acetylcholinesterase on magnetic microbeads using either colo... |
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Risk assessment of pesticides detected in surface water of the Alqueva reservoir (Guadiana basin, southern of Portugal).
Sci. Total Environ. 488-489 , 208-19, (2014) The purpose of this study was to evaluate the potential impact of the pesticides detected in the Alqueva reservoir (Guadiana Basin, South Iberian Peninsula) on the aquatic organisms belonging to this ecosystem. For this purpose, the occurrence and risk assess... |
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Albumin binding as a potential biomarker of exposure to moderately low levels of organophosphorus pesticides.
Biol. Cell 13 , 343-63, (2008) We have evaluated the potential of plasma albumin to provide a sensitive biomarker of exposure to commonly used organophosphorus pesticides in order to complement the widely used measure of acetylcholinesterase (AChE) inhibition. Rat or human plasma albumin b... |
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Extensive Ace2 duplication and multiple mutations on Ace1 and Ace2 are related with high level of organophosphates resistance in Aphis gossypii.
Environ. Toxicol. 29(5) , 526-33, (2014) Aphis gossypii (Glover) has been found to possess multiple mutations in the acetylcholinesterase (AChE) gene (Ace) that might involve target site insensitivity. In vitro functional expression of AChEs reveals that the resistant Ace1 (Ace1R) and Ace2 (Ace2R) w... |
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Detoxification of organophosphate residues using phosphotriesterase and their evaluation using flow based biosensor.
Anal. Chim. Acta 745 , 64-9, (2012) Among known pesticide groups, organophosphates (OPs) have grasped attention due to their hazardous nature and their applications as pesticides and chemical weapons. This work presents the development of cost-effective column based biosensor for detoxification... |
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Probing the chiral separation mechanism and the absolute configuration of malathion, malaoxon and isomalathion enantiomers by chiral high performance liquid chromatography coupled with chiral detector-binding energy computations.
J. Chromatogr. A. 1281 , 26-31, (2013) Chiral separation mechanism determination and absolute configuration assignment are fundamental to the development of chiral stationary phases (CSPs) and the evaluation of both the enantioselective bioactivity and fate of chiral compounds. This work investiga... |
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Investigations of kinetic interactions between lipid emulsions, hydroxyethyl starch or dextran and organophosphorus compounds.
Clin. Toxicol. (Phila.) 51(10) , 918-22, (2013) Numerous studies demonstrated a limited efficacy of clinically used oximes in case of poisoning by various organophosphorus compounds. A broad spectrum oxime antidote covering all organophosphorus nerve agents and pesticides is still missing and effective (bi... |
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Further assessment of an in vitro screen that may help identify organophosphorus pesticides that are more acutely toxic to the young.
J. Toxicol. Environ. Health A 67(18) , 1477-89, (2004) Some, but not all, organophosphorus pesticides are more acutely toxic to the young as compared to adults. We have developed an in vitro assay that measures the detoxification potential (via carboxylesterase and A-esterases) of tissues. Previous results using ... |
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Plasma esterases in the tegu lizard Tupinambis merianae (Reptilia, Teiidae): impact of developmental stage, sex, and organophosphorus in vitro exposure.
Environ. Sci. Pollut. Res. Int. 19(1) , 214-25, (2012) In this study, we determined normal serum butyrylcholinesterase (BChE) and carboxylesterase (CbE) activities in Tupinambis merianae in order to obtain reference values for organophosphorus pesticide monitoring.Forty-two T. merianae individuals were grouped by... |
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Mechanism of inhibition of lysyl hydroxylase activity by the organophosphates malathion and malaoxon.
Toxicol. Appl. Pharmacol. 176(3) , 181-6, (2001) Direct inhibition of lysyl hydroxylase by malathion and malaoxon was observed in an in vitro enzyme assay with recombinant lysyl hydroxylase expressed via a baculoviral system. The IC50 values for malathion and malaoxon were estimated to be approximately 60 a... |