卡维地洛

Probiotics Antimicrob Proteins 6 , 141-56, (2014)

This study evaluated the probiotic properties (stability at different pH values and bile salt concentration, auto-aggregation and co-aggregation, survival in the presence of antibiotics and commercial drugs, study of β-galactosidase production, evaluation of ...

Eur. J. Pharm. Sci. 68 , 36-42, (2015)

Naringin is considered the major causative ingredient of the inhibition of intestinal drug uptake by grapefruit juice. Moreover, it is contained in highly dosed nutraceuticals available on the market. A controlled, open, randomized, crossover study was perfor...

Eur. J. Pharm. Sci. 63 , 178-86, (2014)

The mixed micelles and vesicles present in the intraluminal environment of the postprandial state exhibit suitable solubilizing capacities for lipophilic drugs. This increase in solubility, however, is accompanied by a decrease in the free fraction caused by ...

J. Chromatogr. A. 1419 , 45-57, (2015)

This study reports the impact of thermal pretreatment between 400 and 1100°C on superficially porous silica particles (e.g. core-shell, fused-core; here abbreviated as SPP silica). The different thermally pretreated SPP silica (400°C, 900°C and 1100°C) were c...

Eur. J. Pharm. Sci. 75 , 101-13, (2015)

The number of poorly water-soluble drug candidates is rapidly increasing; this represents a major challenge for the pharmaceutical industry. As a consequence, novel formulation approaches are required. Furthermore, if such a drug candidate is intended for the...

J. AOAC Int. 96(5) , 951-9, (2013)

A novel, fast, sensitive, and specific capillary electrophoresis (CE) technique coupled to a diode array detector has been developed for the separation and simultaneous determination of carvedilol (CRV) and hydrochlorothiazide (HCT) in two combination formula...

J. Chromatogr. A. 1388 , 207-16, (2015)

Homochiral metal-organic frameworks (MOFs) are promising as porous stationary phase for open-tubular capillary electrochromatography (OT-CEC) enantioseparation owing to their fine-tuned pore sizes and large surface areas. In this work, the homochiral MOF AlaZ...

J. Control. Release 200 , 167-78, (2015)

Diverse array of therapeutic regimens, drugs or siRNA, are commonly used to regress cardiac hypertrophy, although, bystander effect and lower retention of bioactive molecules significantly reduce their functional clinical efficacy. Carvedilol, a widely used a...

J. Pharm. Biomed. Anal. 111 , 333-43, (2015)

Supercritical fluid chromatography (SFC) is drawing considerable interest as separation technique in the pharmaceutical industry. The technique is already well established in chiral separations both analytically and on a preparative scale. The use of SFC as a...

World J. Gastroenterol. 21 , 9566-76, (2015)

To investigate the effect of carvedilol on angiogenesis and the underlying signaling pathways.The effect of carvedilol on angiogenesis was examined using a human umbilical vascular endothelial cell (HUVEC) model. The effect of carvedilol on cell viability was...