二异丙醇胺

一般危化品
二异丙醇胺结构式
二异丙醇胺结构式
常用名 二异丙醇胺 英文名 UNII:0W44HYL8T5
CAS号 110-97-4 分子量 133.189
密度 1.0±0.1 g/cm3 沸点 254.4±15.0 °C at 760 mmHg
分子式 C6H15NO2 熔点 42-45 °C(lit.)
MSDS 中文版 美版 闪点 126.7±0.0 °C
符号 GHS07
GHS07
信号词 Warning

Effect of diisopropanolamine upon choline uptake and phospholipid synthesis in Chinese hamster ovary cells.

Food Chem. Toxicol. 46(2) , 761-6, (2008)

Aminoalcohols differ in mammalian toxicity at least in part based upon their ability to alter the metabolism of phospholipids and to cause depletion of the essential nutrient choline in animals. This study examined the incorporation of diisopropanolamine (DIP...

Low expression of spindle checkpoint protein, Cenp-E, causes numerical chromosomal abnormalities in HepG-2 human hepatoma cells.

Oncol. Lett. 10 , 2699-2704, (2016)

The aim of the present study was to investigate the expression, localization and role of centromere-associated protein E (Cenp-E) in hepatoma cells. The Cenp-E mRNA expression levels in the HepG-2 human hepatocellular carcinoma and LO2 normal hepatic cell lin...

Triple allergic contact sensitivities due to ferbinac, crotamiton and diisopropanolamine.

Contact Dermatitis 49(5) , 261-3, (2003)

Contact dermatitis due to diisopropanolamine.

Contact Dermatitis 21(1) , 56, (1989)

Carcinogenic activity of endogenously synthesized N-nitrosobis(2-hydroxypropyl)amine in rats administered bis(2-hydroxypropyl)amine and sodium nitrite.

Carcinogenesis 10(9) , 1607-11, (1989)

The carcinogenic activity of endogenously synthesized N-nitrosobis(2-hydroxypropyl)amine (BHP) was investigated in male Wistar rats administered bis(2-hydroxypropyl)amine (BHPA) mixed in powder diet at a concentration of 1%, and sodium nitrite (SN) dissolved ...

Microbial mineralization of diisopropanolamine.

Can. J. Microbiol. 45(5) , 377-88, (1999)

Diisopropanolamine (DIPA) is a "sweetening agent" used to remove hydrogen sulfide from sour natural gas, and it is a contaminant at some sour gas treatment facilities in western Canada. To investigate the biodegradation of this alkanolamine, 14C-DIPA was used...

Initiation activity of endogenously synthesized N-nitrosobis(2-hydroxypropyl)amine in the rat liver.

Cancer Lett. 45(3) , 221-5, (1989)

The initiation potential of N-nitrosobis(2-hydroxypropyl)amine (NDHPA) endogenously synthesized from bis(2-hydroxypropyl)amine (DHPA) or tris(2-hydroxypropyl)amine (THPA) in the presence of sodium nitrite (NaNO2) was investigated in the rat liver by quantitat...

Repeated dose toxicity and developmental toxicity of diisopropanolamine to rats.

Food Chem. Toxicol. 45(10) , 1838-45, (2007)

The repeated dose oral and dermal toxicity of diisopropanolamine (DIPA) was evaluated in rats and compared to the reported toxicity of the related secondary alcohol amine, diethanolamine (DEA). Fischer 344/DuCrl rats were given up to 750 mg/kg/day by dermal a...

Pharmacokinetics and bioavailability of diisopropanolamine (DIPA) in rats following intravenous or dermal application.

Food Chem. Toxicol. 45(10) , 2047-56, (2007)

This study was conducted to determine the relative dermal bioavailability (absorption), distribution, metabolism, and excretion (ADME) of diisopropanolamine (DIPA), an alcohol amine used in a number of industrial and personal care products. Groups of 4 female...

Carcinogenic activity of endogenously synthesized N-nitrosobis(2-hydroxypropyl)amine in rats.

IARC Sci. Publ. (105) , 318-21, (1991)

The carcinogenic activity of endogenously synthesized N-nitroso-bis(2-hydroxy-propyl)amine (NDHPA) was investigated in male Wistar rats administered bis(2-hydroxypropyl)amine (DHPA), mixed into a powdered diet at a concentration of 1%, and NaNO2 dissolved in ...