甲苯-2,4-二异氰酸酯

一般危化品
甲苯-2,4-二异氰酸酯结构式
甲苯-2,4-二异氰酸酯结构式
常用名 甲苯-2,4-二异氰酸酯 英文名 toluene 2,4-diisocyanate
CAS号 584-84-9 分子量 174.156
密度 1.1±0.1 g/cm3 沸点 251.0±0.0 °C at 760 mmHg
分子式 C9H6N2O2 熔点 20-22 °C(lit.)
MSDS 中文版 美版 闪点 110.5±30.7 °C
符号 GHS06 GHS08
GHS06, GHS08
信号词 Danger

Incorporation of electrochemical advanced oxidation processes in a multistage treatment system for sanitary landfill leachate.

Water Res. 81 , 375-87, (2015)

The current study has proved the technical feasibility of including electrochemical advanced oxidation processes (EAOPs) in a multistage strategy for the remediation of a sanitary landfill leachate that embraced: (i) first biological treatment to remove the b...

Multiple shape memory polymers based on laminates formed from thiol-click chemistry based polymerizations.

Soft Matter 11 , 6852-8, (2015)

This investigation details the formation of polymer network trilayer laminates formed by thiol-X click chemistries, and their subsequent implementation and evaluation for quadruple shape memory behavior. Thiol-Michael addition and thiol-isocyanate-based cross...

Prevalence and outcome of diastolic dysfunction in liver transplantation recipients.

Acta Cardiol. 69(3) , 273-80, (2014)

Cirrhotic cardiomyopathy (CCMP) denotes a chronic cardiac dysfunction in cirrhotic patients. It is characterized by systolic (SD) and diastolic dysfunction (DD), and electromechanical abnormalities, in the absence of other cardiac diseases. Liver transplantat...

Phosphatidylinositol 3-Kinase Mediates β-Catenin Dysfunction of Airway Epithelium in a Toluene Diisocyanate-Induced Murine Asthma Model.

Toxicol. Sci. 147 , 168-77, (2015)

Cell-cell junctions are critical for the maintenance of cellular as well as tissue polarity and integrity. Yet the role of phosphatidylinositol 3-kinase (PI3K) in dysregulation of airway epithelial adherens junctions in toluene diisocyanate (TDI)-induced asth...

Topically Administered Janus-Kinase Inhibitors Tofacitinib and Oclacitinib Display Impressive Antipruritic and Anti-Inflammatory Responses in a Model of Allergic Dermatitis.

J. Pharmacol. Exp. Ther. 354 , 394-405, (2015)

The prevalence of allergic skin disorders has increased rapidly, and development of therapeutic agents to alleviate the symptoms are still needed. In this study, we orally or topically administered the Janus kinase (JAK) inhibitors, tofacitinib and oclacitini...

Phosphatidylinositol 3-kinases pathway mediates lung caspase-1 activation and high mobility group box 1 production in a toluene-diisocyanate induced murine asthma model.

Toxicol. Lett. 236 , 25-33, (2015)

We have previously demonstrated that downregulating HMGB1 decreases airway neutrophil inflammation in a toluene-diisocyanate (TDI)-induced murine asthma model, yet how HMGB1 is regulated in the lung remains uncertain. In this study, we intended to explore whe...

1,25-Dihydroxyvitamin D3 prevents toluene diisocyanate-induced airway epithelial barrier disruption.

Int. J. Mol. Med. 36 , 263-70, (2015)

The loss of airway epithelial integrity contributes significantly to asthma pathogenesis. Evidence suggests that vitamin D plays an important role in the prevention and treatment of asthma. However, its role in airway epithelial barrier function remains uncer...

Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.

J. Med. Chem. 53 , 5085-107, (2010)

Assessment of antifouling efficacy of polyhedral oligomeric silsesquioxane based poly (urea-urethane-imide) hybrid membranes.

Lett. Appl. Microbiol. 61 , 274-82, (2015)

A series of polyhedral oligomeric silsesquioxane (POSS) based poly(urea-urethane-imide) (PUUI-POSS) membranes were synthesized by varying the proportions of imide using 2,4-toluene diisocyanate (TDI) and bis(aminopropyl) terminated polydimethylsiloxane (PDMS)...

A method for determining reactive hydroxyl groups in natural fibers: application to ramie fiber and its modification.

Carbohydr. Res. 348 , 95-8, (2012)

The hydrophilic features of natural fibers (NFs) hinder the widespread application of natural fiber/polymer composites due to the hydroxyl groups (-OH) presented in the cellulose molecule. Detecting reactive hydroxyl groups in NFs is very important for optimi...