6-甲基-4-羟基-2-吡喃酮

6-甲基-4-羟基-2-吡喃酮结构式
6-甲基-4-羟基-2-吡喃酮结构式
品牌特惠专场
常用名 6-甲基-4-羟基-2-吡喃酮 英文名 triacetate lactone
CAS号 675-10-5 分子量 126.11
密度 1.3±0.1 g/cm3 沸点 239.1±40.0 °C at 760 mmHg
分子式 C6H6O3 熔点 188-190 °C (dec.)(lit.)
MSDS 美版 闪点 108.7±20.1 °C
符号 GHS07
GHS07
信号词 Warning

Purification and properties of 6-methylsalicylic acid synthase from Penicillium patulum.

Biochem. J. 288 ( Pt 3) , 839-46, (1992)

6-Methylsalicylic acid synthase has been isolated in homogeneous form from Penicillium patulum grown in liquid culture from a spore inoculum. The enzyme is highly susceptible to proteolytic degradation in vivo and in vitro, but may be stabilized during purifi...

Microbial synthesis of triacetic acid lactone.

Biotechnol. Bioeng. 93(4) , 727-36, (2006)

Native g2ps1-encoded 2-pyrone synthase (2-PS) from Gerbera hybrida, a mutant Brevibacterium ammoniagenes fatty acid synthase B (FAS-B) and two different mutants of Penicillium patulum 6-methylsalycilic acid synthase (6-MSAS) are examined to identify the best ...

Rational pathway engineering of type I fatty acid synthase allows the biosynthesis of triacetic acid lactone from D-glucose in vivo.

J. Am. Chem. Soc. 126(14) , 4534-5, (2004)

Metabolic pathway engineering is a powerful tool to synthesize structurally diverse and complex chemicals via genetic manipulation of multistep catalytic systems involved in cell metabolism. Here, we report the rational design of a fatty acid biosynthetic pat...

Effect of NADPH-associated keto-reducing domain on substrate entry into 6-hydroxymellein synthase, a multifunctional polyketide synthetic enzyme involved in phytoalexin biosynthesis in carrot.

Arch. Biochem. Biophys. 328(1) , 213-7, (1996)

6-Hydroxymellein synthase is a polyketide biosynthetic enzyme induced in carrot cells which is organized as a homodimer composed of multifunctional subunits. The synthase liberates triacetic acid lactone, instead of 6-hydroxymellein, as a derailment product w...

Crystallization and preliminary X-ray diffraction studies of polyketide synthase-1 (PKS-1) from Cannabis sativa.

Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 64(Pt 3) , 217-20, (2008)

Polyketide synthase-1 (PKS-1) is a novel type III polyketide synthase that catalyzes the biosynthesis of hexanoyl triacetic acid lactone in Cannabis sativa (Mexican strain). PKS-1 was overproduced in Escherichia coli, purified and finally crystallized in two ...

Synthesis of acetoacetyl-CoA by bovine mammary fatty acid synthase.

FEBS Lett. 132(2) , 231-4, (1981)

Irreversible inactivation of chicken liver fatty acid synthetase by its substrates acetyl and malonyl CoA. Effect of temperature and NADP n fatty acid and triacetic acid lactone synthesis.

Biochem. Biophys. Res. Commun. 99(3) , 920-7, (1981)