硝酸异丁酯结构式
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常用名 | 硝酸异丁酯 | 英文名 | isobutyl nitrate |
|---|---|---|---|---|
| CAS号 | 543-29-3 | 分子量 | 119.11900 | |
| 密度 | 1.044g/cm3 | 沸点 | 124.3ºC at 760mmHg | |
| 分子式 | C4H9NO3 | 熔点 | -111.59°C (estimate) | |
| MSDS | 中文版 美版 | 闪点 | 40.9ºC | |
| 符号 |
GHS02, GHS07 |
信号词 | Danger |
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Vibrational analysis of isopropyl nitrate and isobutyl nitrate.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 58(12) , 2571-80, (2002) Raman and infrared spectra of isopropyl nitrate and isobutyl nitrate are reported. These spectra are used in combination with computational studies employing density functional theory at the B3-LYP/6-31G* level to assign the vibrational transitions to their c... |
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Inflammatory macrophage nuclear factor-kappaB and proteasome activity are inhibited following exposure to inhaled isobutyl nitrite.
J. Leukoc. Biol. 69(4) , 639-44, (2001) A history of abuse of nitrite inhalants has been correlated with HIV seropositivity and Kaposi's sarcoma. A series of 14 daily, 45-min exposures of mice to 900-ppm isobutyl nitrite in an inhalation chamber reduced the number of peritoneal exudate macrophages ... |
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Research shows 'poppers' use in connected with infection among MSM. Little is done to address problem.
AIDS Alert 19(6) , 61, 63-4, (2004) Researchers and experts on the use of inhaled nitrates among men who have sex with men (MSM) say clinicians, public health officials, and AIDS groups are ignoring the impact of poppers, a popular party inhalant, on HIV risk behaviors and even seroconversion. |
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Prechronic inhalation toxicity studies of isobutyl nitrite.
Fundam. Appl. Toxicol. 19(2) , 169-75, (1992) Isobutyl nitrite (IBN) is a volatile liquid that has become increasingly popular as an inhaled recreational drug. To investigate short-term toxic effects and establish exposure parameters for chronic inhalation studies, F344/N rats and B6C3F1 mice were expose... |
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Comparison of isobutyl nitrate and isobutyl nitrite: tolerance and cross-tolerance to glyceryl trinitrate.
Eur. J. Pharmacol. 192(1) , 181-4, (1991) This study includes the first systematic comparison of an organic nitrate with the corresponding organic nitrite-isobutyl nitrate and isobutyl nitrite. The spasmolytic activity of the nitrite on isolated rabbit aortic strips was stronger, more rapid in onset,... |
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Inhaled isobutyl nitrite inhibited macrophage inducible nitric oxide by blocking NFkappaB signaling and promoting degradation of inducible nitric oxide synthase-2.
Int. Immunopharmacol. 4(8) , 1075-82, (2004) We previously reported that inhaled isobutyl nitrite inhibited macrophage tumoricidal activity by inhibiting inducible nitric oxide (NO) production. In the present study, a much shorter inhalant exposure regimen (five daily exposures) inhibited inducible NO a... |
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Direct demonstration of NO formation in vivo from organic nitrites and nitrates, and correlation to effects on blood pressure and to in vitro effects. Cederqvist B, et al.
Biochem. Pharmacol. 47(6) , 1047-1053, (1994)
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Formation and thermal decomposition of butyl-substituted peroxyacyl nitrates: n-C4H9C(O) OONO2 and i-C4H9C(O)OONO2. Grosjean D, et al.
Environ. Sci. Technol. 28(6) , 1099-1105, (1994)
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