2-氨基嘌呤 硝酸盐结构式
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常用名 | 2-氨基嘌呤 硝酸盐 | 英文名 | 2-AP nitrate salt |
|---|---|---|---|---|
| CAS号 | 51-16-1 | 分子量 | 198.14000 | |
| 密度 | N/A | 沸点 | 616.3ºC at 760 mmHg | |
| 分子式 | C5H6N6O3 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 362.9ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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IL-10-dependent S100A8 gene induction in monocytes/macrophages by double-stranded RNA.
J. Immunol. 182 , 2258-2268, (2009) The S100 calcium-binding proteins S100A8 and S100A9 are elevated systemically in patients with viral infections. The S100A8-S100A9 complex facilitated viral replication in human CD4(+) T lymphocytes latently infected with HIV-1- and S100A8-induced HIV-1 trans... |
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Novel role for the double-stranded RNA-activated protein kinase PKR: modulation of macrophage infection by the protozoan parasite Leishmania.
FASEB J. 24 , 617-626, (2010) The evolution of Leishmania infection depends on the balance between microbicidal and suppressor macrophage functions. Double-stranded RNA (dsRNA)-activated protein kinase R (PKR), a classic antiviral protein, is able to regulate a number of signaling pathway... |
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Activation of protein kinase R is required for induction of stress granules by respiratory syncytial virus but dispensable for viral replication.
Virology 413 , 103-110, (2011) We performed experiments to determine the effect of PKR activation on respiratory syncytial virus (RSV) replication. We first determined that RSV infection activates PKR which induces the phosphorylation of eIF2α, resulting in the formation of host stress gra... |
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Double stranded RNA-dependent protein kinase is involved in osteoclast differentiation of RAW264.7 cells in vitro
Exp. Cell Res. 316 , 3254-3262, (2010) Double-stranded RNA-dependent protein kinase (PKR) plays a critical role in antiviral defence of the host cells. PKR is also involved in cell cycle progression, cell proliferation, cell differentiation, tumorigenesis, and apoptosis. We previously reported tha... |
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Molecules involve in the self-protection of neurons against glucose-oxygen-serum deprivation (GOSD)-induced cell damage.
Brain Res. Bull. 79 , 169-76, (2009) Molecules involved in self-protection of neurons against glucose/oxygen/serum deprivation (GOSD) were investigated. Trypan blue dye exclusion assay, Western blotting, ELISA, cytokine antibody array and chemical blocking assay were applied in the study. Result... |