琼脂糖

Endocrinology 156 , 2162-73, (2015)

The neuropeptide kisspeptin is essential for sexual maturation and reproductive function. In particular, kisspeptin-expressing neurons in the anterior rostral periventricular area of the third ventricle are generally recognized as mediators of estrogen positi...

Oncotarget 6 , 16488-506, (2015)

Malignant melanoma is the most dangerous type of skin cancer. Although recent progress in treatment has been achieved, lack of response, drug resistance and relapse remain major problems. The tumor suppressor p53 is rarely mutated in melanoma, yet it is inact...

Biosens. Bioelectron. 74 , 360-8, (2015)

A novel polymerase chain reaction (PCR) device was developed that uses wire-guided droplet manipulation (WDM) to guide a droplet over three different heating chambers. After PCR amplification, end-point detection is achieved using a smartphone-based fluoresce...

J. Mol. Biol. 427(2) , 387-405, (2015)

eIF4E1b, closely related to the canonical translation initiation factor 4E (eIF4E1a), cap-binding protein is highly expressed in mouse, Xenopus and zebrafish oocytes. We have previously characterized eIF4E1b as a component of the CPEB mRNP translation repress...

Rev. Sci. Instrum. 86 , 075005, (2015)

Abnormal blood clot stiffness is an important indicator of coagulation disorders arising from a variety of cardiovascular diseases and drug treatments. Here, we present a portable instrument for elastometry of microliter volume blood samples based upon the pr...

J. Biosci. Bioeng. 117(4) , 497-500, (2014)

Agarose gels were superior to calcium-alginate gels for immobilizing Rhodococcus erythropolis CS98 strain to remove cesium from water. Suitable incubation time of the immobilized cells in cesium solutions, cell number in the gels and volume ratio of the cesiu...

J. Bacteriol. 191(4) , 1169-79, (2009)

Ribonucleotide reductases (RNRs) are essential enzymes in all living cells, providing the only known de novo pathway for the biosynthesis of deoxyribonucleotides (dNTPs), the immediate precursors of DNA synthesis and repair. RNRs catalyze the controlled reduc...

Exp. Parasitol. 140 , 33-8, (2014)

Benznidazole (Bzn) is a nitroimidazole drug currently used as first line treatment against Chagas disease, a neglected tropical disease caused by the flagellated protozoan Trypanosoma cruzi. Although the drug has been used since the late 1960s, its mechanism ...

J. Nanosci. Nanotechnol. 14(6) , 4257-63, (2014)

In this study, a novel approach to tailor the calcium carbonate nanoparticles was exploited based on agarose gel as polymer medium. The size of nanoparticles formed was governed by ionic diffusion and affected by weight percent of agarose and reaction tempera...

Biochim. Biophys. Acta 1850(1) , 22-32, (2015)

Dopamine neurons derived from induced pluripotent stem cells have been widely studied for the treatment of Parkinson's disease. However, various difficulties remain to be overcome, such as tumor formation, fragility of dopamine neurons, difficulty in handling...