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4-(2-氨乙基)苯磺酰胺

4-(2-氨乙基)苯磺酰胺结构式
4-(2-氨乙基)苯磺酰胺结构式
品牌特惠专场
常用名 4-(2-氨乙基)苯磺酰胺 英文名 4-(2-aminoethyl)benzene sulfonmide
CAS号 35303-76-5 分子量 200.258
密度 1.3±0.1 g/cm3 沸点 387.4±44.0 °C at 760 mmHg
分子式 C8H12N2O2S 熔点 150-152 °C(lit.)
MSDS 中文版 美版 闪点 188.1±28.4 °C

Multiple ligand detection and affinity measurement by ultrafiltration and mass spectrometry analysis applied to fragment mixture screening.

Anal. Chim. Acta 886 , 98-106, (2015)

Binding affinity of a small molecule drug candidate to a therapeutically relevant biomolecular target is regarded the first determinant of the candidate's efficacy. Although the ultrafiltration-LC/MS (UF-LC/MS) assay enables efficient ligand discovery for a s...

Inhibition of hypoxia-inducible carbonic anhydrase-IX enhances hexokinase II inhibitor-induced hepatocellular carcinoma cell apoptosis.

Acta Pharmacol. Sin. 32(7) , 912-20, (2011)

The hypoxic condition within large or infiltrative hypovascular tumors produces intracellular acidification, which could activate many signaling pathways and augment cancer cell growth and invasion. Carbonic anhydrase-IX (CA-IX) is an enzyme lowering pH. This...

Probing protein binding spectra with Fourier microfluidics.

Conf. Proc. IEEE Eng. Med. Biol. Soc. 2010 , 5318-21, (2010)

New developments in microfluidic chip technology enable the construction of chemical spectrum analyzers that can probe the binding interactions between chemical entities. In this paper we report the implementation of a microfluidic chip suitable for Fourier t...

Low noise detection of biomolecular interactions with signal-locking surface plasmon resonance.

Anal. Chem. 82(14) , 6025-31, (2010)

Surface plasmon resonance (SPR) is a popular technique for label-free detection of biomolecular interactions at a surface. SPR yields quantitative kinetic association and dissociation constants of surface interactions such as the binding of two molecular spec...

Serine protease inhibitors block priming of monocytes for enhanced release of superoxide.

Immunology 86(4) , 629-35, (1995)

Monocytes freshly isolated from human blood produced large amounts of superoxide when triggered by phorbol ester. After monocytes were cultured for 18-24 hr in endotoxin-free, non-adherent conditions, they produced low amounts of superoxide. Addition of lipop...