汉黄芩苷结构式
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常用名 | 汉黄芩苷 | 英文名 | Wogonoside |
|---|---|---|---|---|
| CAS号 | 51059-44-0 | 分子量 | 460.388 | |
| 密度 | 1.6±0.1 g/cm3 | 沸点 | 869.0±65.0 °C at 760 mmHg | |
| 分子式 | C22H20O11 | 熔点 | 226-227ºC | |
| MSDS | 美版 | 闪点 | 304.0±27.8 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Extraction and Bioactivity Analysis of Major Flavones Compounds from Scutellaria baicalensis Using In Vitro Assay and Online Screening HPLC-ABTS System.
J. Anal. Methods Chem. 2014 , 563702, (2014) The extraction efficiency of a number of solvent compositions for the improvement of bioactive compounds yield from S. baicalensis has been investigated. Also, free radical scavengers in the glycoside baicalin (BG), wogonoside (WG), aglycon baicalein (B), and... |
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Wogonoside induces autophagy-related apoptosis in human glioblastoma cells.
Oncol. Rep. 32(3) , 1179-87, (2014) Wogonoside, a bioactive flavonoid extracted from the root of Scutellaria baicalensis Georgi, has shown preclinical anticancer efficacy in various cancer models. However, the effects of wogonoside on glioblastoma cells remain unclear. In the present study, we ... |
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Liquid Chromatography-Tandem Mass Spectrometry Screening Method for the Detection of Radical-Scavenging Natural Antioxidants from the Whole Scutellariae (Radix, Stem and Leaf).
J. Chromatogr. Sci. 53 , 1140-6, (2015) A novel free radical reaction combined with high-performance LC-photodiode array-ESI-MS/MS screening method was developed for the detection and identification of natural antioxidants from whole Scutellariae. Six compounds and whole Scutellariae extracts were ... |
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Simultaneous determination of various bioactive redox components in Shuang–Huang–Lian preparations using a novel three-channel isocratic elution liquid chromatography with electrochemical detection system
J. Pharm. Biomed. Anal. 95 , 93-101, (2014) A novel three-channel isocratic elution high performance liquid chromatography with electrochemical detection (3LC-ECD) system was developed for the simultaneous determination of various bioactive redox components in Shuang-Huang-Lian (SHL) preparations. This... |
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Studies on the antioxidant properties of extracts from the roots and shoots of two Scutellaria species in human blood plasma.
Acta Biochim. Pol. 62 , 253-8, (2015) We determined the in vitro antioxidant activity of methanolic extracts from the shoots and roots of Scutellaria species (S. altissima and S. alpina) against the action of strong oxidants: hydrogen peroxide (H2O2) and H2O2+Fe(2+) (donor of hydroxyl radicals) o... |
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Cloning and expression of beta-glucuronidase from Lactobacillus brevis in E. coli and application in the bioconversion of baicalin and wogonoside.
J. Microbiol. Biotechnol. 19(12) , 1650-5, (2009) The beta-glucuronidase (GUS) gene from Lactobacillus brevis RO1 was cloned and expressed in Escherichia coli GMS407. The GUS gene was composed of 1812 bp, encoding a 603-amino-acid protein belonging to the glycosyl hydrolase family 2 with three conserved doma... |
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Effect of light, methyl jasmonate and cyclodextrin on production of polyphenolic compounds in hairy root cultures of Scutellaria lateriflora
Phytochemistry 107 , 50-60, (2014) Graphical abstract [Display omitted] |
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Antithrombotic activities of wogonin and wogonoside via inhibiting platelet aggregation.
Fitoterapia 98 , 27-35, (2014) Wogonin (WGN), a flavonoid extracted from Scutellaria baicalensis Georgi, has several biological effects including antioxidant, anti-inflammatory, antiviral, neuroprotective, anxiolytic, and anticancer activities, and the flavonoid wogonoside (WGNS) can be de... |
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Comparative pharmacokinetics of baicalin after oral administration of pure baicalin, Radix scutellariae extract and Huang-Lian-Jie-Du-Tang to rats.
J. Ethnopharmacol. 110(3) , 412-8, (2007) Huang-Lian-Jie-Du-Tang (HLJDT) is an important "heat-clearing" multiherb remedy of traditional Chinese medicine, and Radix scutellariae (Scutellaria baicalensis Georgi, Labiatae) is a key ingredient herb in it. Baicalin and wogonoside are two main effective i... |
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Separation and purification of baicalin and wogonoside from the Chinese medicinal plant Scutellaria baicalensis Georgi by high-speed counter-current chromatography.
J. Chromatogr. A. 1066(1-2) , 243-7, (2005) A preparative high-speed counter-current chromatography (HSCCC) method for isolation and purification of baicalin and wogonoside from the Chinese medicinal plant Scutellaria baicalensis Georgi (Huang-qin in Chinese) was successfully established by using ethyl... |